Bifidobacterium bifidum

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium bifidum is a mesophilic, chemoheterotrophic, Gram-positive bacterium that exhibits a rod-shaped morphology and is primarily found in the human gastrointestinal tract, particularly in feces, as well as in the oral cavity and vagina. This microbe thrives in anaerobic environments, making it an obligate anaerobe, which means it cannot survive in the presence of oxygen. Its metabolism is reliant on fermentative processes, allowing it to extract energy from a variety of carbohydrates, particularly dietary fibers and oligosaccharides, which it ferments to produce organic acids, primarily lactic acid and acetic acid. These fermentation products contribute to the acidic environment of the gut, inhibiting the growth of harmful pathogens. Bifidobacterium bifidum plays a critical role in maintaining gut health and promoting a balanced microbiome. It is often considered a probiotic due to its beneficial effects on digestion and overall health. This bacterium helps in the breakdown of complex carbohydrates, facilitates nutrient absorption, and enhances immune function by stimulating the production of antibodies and modulating inflammatory responses.In addition to its role in gut health, Bifidobacterium bifidum is also recognized for its potential therapeutic applications. It has been studied for its effects on alleviating symptoms of irritable bowel syndrome (IBS), diarrhea, and constipation. Furthermore, its presence in yogurt and other fermented foods highlights its importance in the food industry, as it contributes to the probiotic content of these products, promoting gut health in consumers. The unique ability of Bifidobacterium bifidum to survive in the human gut and exert beneficial effects makes it a focal point of research in microbiome studies and probiotic formulation.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium bifidum
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Bifidobacterium bifidum
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Rodentia
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium bifidum strain AM12-10 AM12-10.Scaf11, whole

Gene Summary

Adenine Count

444823 bp

Thymine Count

444832 bp

Guanine Count

739840 bp

Cytosine Count

745841 bp

Genome Length

2375485 bp

Protein-coding Genes

1864 genes

Non-Coding Genes

116 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
rok family proteinNCTC10471_00843Not AvailablePositive917394 - 91860242334.3
putative alpha-galactosidaseNCTC10471_00844Not AvailableNegative918715 - 92103084114.3
cytidine and deoxycytidylate deaminase zinc-binding regionNCTC10471_00845Not AvailableNegative921147 - 92158115055.0
putative na+/h+ antiporterNCTC10471_00846Not AvailablePositive922030 - 92410275713.6
sulfite exporter taue/safe domain proteinNCTC10471_00847Not AvailableNegative924144 - 92494727975.3
serine hydrolaseNCTC10471_00848Not AvailableNegative925059 - 92581727630.4
proteinNCTC10471_00849Not AvailableNegative925875 - 92674430342.4
deoxycytidine triphosphate deaminaseNCTC10471_00850Not AvailablePositive927101 - 92768221491.3
sugar-binding domain-containing proteinNCTC10471_00851Not AvailablePositive927745 - 92912447444.3
putative potassium/sodium efflux p-type atpase, fungal-typeNCTC10471_00852Not AvailableNegative929214 - 932204105429.0

Displaying genes 2851 – 2860 of 4278 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
GhCausesPMC10522390

Displaying health effects 1 – 1 of 1 in total