Paraclostridium bifermentans

Gram-positiveRodNon-motileAnaerobic

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Peptostreptococcales

Family

Peptostreptococcaceae

Genus

Paraclostridium

Description

Paraclostridium bifermentans is a Gram-positive, rod-shaped microbe that thrives in mesophilic temperatures, categorized as a Chemoheterotroph, and can be found in various body sites, including the gastrointestinal tract, skin, and respiratory tract, of numerous species, including humans, animals, and insects. As an Obligate Anaerobe, P. bifermentans requires a strict anaerobic environment to grow, which is reflected in its inability to survive in the presence of oxygen. The Gram-positive cell wall of P. bifermentans provides it with a robust structural framework, while its rod-shaped morphology allows for efficient movement and colonization in its host. As a Chemoheterotroph, P. bifermentans relies on the breakdown of organic compounds to obtain energy, which is consistent with its presence in environments rich in organic matter. The mesophilic temperature preference of P. bifermentans indicates that it is well-suited to grow in temperatures ranging from 20-45°C, which is typical of many environments, including the human body. P. bifermentans has been implicated in various diseases, including gas gangrene and bacteremia, highlighting the importance of understanding its biology and ecology. The microbe's ability to produce toxins and fermented products has led to its exploration in biotechnological applications, such as the production of biofuels and other valuable compounds.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderPeptostreptococcales
FamilyPeptostreptococcaceae
GenusParaclostridium
SpeciesParaclostridium bifermentans
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Paraclostridium bifermentans
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatAnimal intestinal microflora
Biotic relationshipNot Available
Host(s)Homo sapiens, Ovis aries, Cavia
Cell arrangementNot Available
SporulationSporulating
Energy sourceChemoheterotroph
PathogenicityNon-pathogenic

Genome Summary

Paraclostridium bifermentans


Gene Summary

Adenine Count

1224979 bp

Thymine Count

1306917 bp

Guanine Count

466292 bp

Cytosine Count

524733 bp

Genome Length

3522921 bp

Protein-coding Genes

3258 genes

Non-Coding Genes

83 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinB2H97_04610Not AvailablePositive999421 - 9996096998.64
fad-dependent oxidoreductaseB2H97_04615Not AvailableNegative999663 - 100098550233.9
hypothetical proteinB2H97_04620Not AvailableNegative1001164 - 100150512445.7
mate family efflux transporterB2H97_04625Not AvailableNegative1001801 - 100317148804.7
marr family transcriptional regulatorB2H97_04630Not AvailableNegative1003249 - 100369216891.6
hypothetical proteinB2H97_04635Not AvailableNegative1003856 - 100478834992.8
glycosyl hydrolaseB2H97_04640Not AvailableNegative1004864 - 100710783695.0
hypothetical proteinB2H97_04645Not AvailableNegative1007357 - 100985297964.6
hypothetical proteinB2H97_04650Not AvailableNegative1010075 - 101038312418.5
hypothetical proteinB2H97_04655Not AvailablePositive1010635 - 101145629908.8

Displaying genes 961 – 970 of 3341 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

14 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000503L-rhamnoseC6H12O5Chemical structure of L-rhamnose3615-41-6
Average164.1565Da
Monoisotopic164.0684735Da
BASm0001848D-lysineC6H14N2O2Chemical structure of D-lysine923-27-3
Average146.19Da
Monoisotopic146.1055277Da
BASm0002051D-fructoseC6H12O6Chemical structure of D-fructose57-48-7
Average180.1559Da
Monoisotopic180.0633881Da
BASm0014032Acetic acidC2H4O2Chemical structure of Acetic acid64-19-7
Average60.052Da
Monoisotopic60.021129372Da
BASm0014033AmmoniaH3NChemical structure of Ammonia7664-41-7
Average17.0305Da
Monoisotopic17.026549101Da
BASm0014043Phenylacetic acidC8H8O2Chemical structure of Phenylacetic acid103-82-2
Average136.1479Da
Monoisotopic136.0524295Da
BASm0014045Propionic acidC3H6O2Chemical structure of Propionic acid79-09-4
Average74.0785Da
Monoisotopic74.036779436Da
BASm0014057Isovaleric acidC5H10O2Chemical structure of Isovaleric acid503-74-2
Average102.1317Da
Monoisotopic102.068079564Da
BASm0014074LevanC18H32O16Chemical structure of Levan9013-95-0
Average504.4371Da
Monoisotopic504.169034976Da
BASm0014079FuranC4H4OChemical structure of Furan110-00-9
Average68.074Da
Monoisotopic68.02621475Da

Displaying 1–10 of 14 metabolites

Health Effects

Health ConditionRelationReference
Fatal infectionsCausesPMC10622607
Brain abscessCausesPMC9449513
LymphadenitisCausesPMC9449513
Necrotizing endometritisCausesPMC9449513
Prosthetic knee joint infectionCausesPMC9449513
EmpyemaCausesPMC9449513
EndocarditisCausesPMC9449513

Displaying health effects 1 – 7 of 7 in total