Lactococcus lactis

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Lactococcus

Description

Lactococcus lactis is a Gram-positive, non-motile coccus that typically forms chains and exhibits a facultative anaerobic lifestyle. This mesophilic bacterium thrives optimally at 40°C, making it well-suited for various warm environments. L. lactis is non-sporulating and possesses a single cellular membrane, which is characteristic of its physiological structure. As a free-living organism, L. lactis occupies multiple habitats, reflecting its versatile nature. It is notable for its non-pathogenic status in humans, positioning it as a safe organism for fermentation processes. The bacterium has two replicons, highlighting its genomic complexity, with accessions MTJS00000000.1 and OGTW00000000.2 available for further genomic studies. In the context of microbial ecology, L. lactis plays a significant role in dairy fermentation, contributing to the production of various fermented dairy products. Its ability to thrive in diverse habitats, coupled with its favorable fermentation traits, underscores its importance in both food production and the study of beneficial microorganisms.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusLactococcus
SpeciesLactococcus lactis
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Lactococcus lactis
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature40
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Bos taurus, Bos
Cell arrangementChains
SporulationNonsporulating
Energy sourceNot Available
PathogenicityHuman; Non-pathogenic

Genome Summary

Lactococcus lactis strain 537 contig_18, whole genome shotgun

Gene Summary

Adenine Count

855302 bp

Thymine Count

840763 bp

Guanine Count

454140 bp

Cytosine Count

446381 bp

Genome Length

2597939 bp

Protein-coding Genes

2350 genes

Non-Coding Genes

147 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Putative uracil permeaseAMHIJAGA_00099Not AvailablePositive105345 - 10663745315.4
aspartate carbamoyltransferaseAMHIJAGA_00100Not AvailablePositive106821 - 10775334560.3
Carbamoyl phosphate synthase small subunitAMHIJAGA_00101Not AvailablePositive107816 - 10888939713.1
AttlNot AvailableNot AvailablePositive108720 - 108731Not Available
IntegraseAMHIJAGA_00102Not AvailableNegative108994 - 11013344109.1
Cl repressorAMHIJAGA_00103Not AvailableNegative110183 - 11099530831.4
hypothetical proteinAMHIJAGA_00104Not AvailableNegative111583 - 11189712180.6
hypothetical proteinAMHIJAGA_00105Not AvailableNegative111911 - 11232115800.3
Cro/cl-like repressorAMHIJAGA_00106Not AvailablePositive112470 - 1127099396.31
Hypothetical proteinAMHIJAGA_00107Not AvailablePositive112721 - 1129036772.92

Displaying genes 1 – 10 of 5585 in total

Metabolites

21 records
Metabolite IDMetabolite nameStructureCAS number
BASm0002051D-fructoseC6H12O6Chemical structure of D-fructose57-48-7
Average180.1559Da
Monoisotopic180.0633881Da
BASm0014032Acetic acidC2H4O2Chemical structure of Acetic acid64-19-7
Average60.052Da
Monoisotopic60.021129372Da
BASm0014039L-Lactic acidC3H6O3Chemical structure of L-Lactic acid79-33-4
Average90.0779Da
Monoisotopic90.031694058Da
BASm0014063Taurodeoxycholic acidC26H45NO6SChemical structure of Taurodeoxycholic acid516-50-7
Average499.704Da
Monoisotopic499.296758867Da
BASm0014068Nicotinic acidC6H5NO2Chemical structure of Nicotinic acid59-67-6
Average123.1094Da
Monoisotopic123.032028409Da
BASm0014071ChitinC24H41N3O16Chemical structure of Chitin1398-61-4
Average627.5928Da
Monoisotopic627.248682279Da
BASm0014109Isocaproic acidC6H12O2Chemical structure of Isocaproic acidNULL
Average116.1583Da
Monoisotopic116.083729628Da
BASm00142534-O-alpha-D-Galactopyranuronosyl-D-galacturonic acidC12H18O13Not availableNULL
Average370.263Da
Monoisotopic370.07474064Da
BASm0016119Lacticin 481C127H182N36O35S4Chemical structure of Lacticin 481NULL
Average2901.31Da
Monoisotopic2899.2451164Da
BASm0016485Lactococcin mmfiiC42H63N15O15SNot availableNULL
Average1050.12Da
Monoisotopic1049.434877563Da

Displaying 1–10 of 21 metabolites

Health Effects

Health ConditionRelationReference
EndocarditisCausesPMC10064683
PeritonitisCausesPMC10064683
Intra-abdominal infectionsCausesPMC10064683
Infectious endocarditisCausesPMC10064683
Hepatic abscessCausesPMC10064683
Liver abscessesCausesPMC10064683
MastitisCausesPMC13343983
LactococcosisCausesPMC12824592

Displaying health effects 1 – 8 of 8 in total