Streptococcus sanguinis

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus sanguinis is a Gram-positive, non-motile coccus that typically forms chains and pairs. This facultative anaerobe thrives in mesophilic temperatures, indicating its adaptation to a moderate temperature range. S. sanguinis is a nonsporulating organism, possessing a single cellular membrane. This species is primarily associated with human hosts and exhibits a free-living biotic relationship. It has been identified with four distinct replicons, which are reflected in its genomic data accessed from multiple sources. The presence of these replicons may contribute to its genetic diversity and adaptability within its ecological niche. Although not characterized as a primary pathogen, S. sanguinis can play a role in human health and disease, particularly in relation to oral microbiota and its potential implications in dental and systemic conditions. The ability of S. sanguinis to exist in both free-living and host-associated states may facilitate its survival and ecological success in varying environments. This duality underscores its importance in both health and disease contexts, as it can contribute to the complex interactions within the human microbiome.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus sanguinis
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus sanguinis
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Oryctolagus cuniculus
Cell arrangementChains - Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus sanguinis strain BCC64 D8875_contig083, whole genome

Gene Summary

Adenine Count

668774 bp

Thymine Count

673657 bp

Guanine Count

502311 bp

Cytosine Count

519568 bp

Genome Length

2370463 bp

Protein-coding Genes

2283 genes

Non-Coding Genes

51 genes

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
l-cystine transport system permease protein tcybD8875_10755Not AvailablePositive2153801 - 215596978627.7
glutamine transport atp-binding protein glnqD8875_10760Not AvailablePositive2155969 - 215670927243.8
d-alanyl-d-alanine carboxypeptidase precursorD8875_10765Not AvailableNegative2156766 - 215854466402.9
d-alanyl-d-alanine carboxypeptidase precursorD8875_10770Not AvailableNegative2158609 - 216039067132.1
caax amino terminal protease self- immunityD8875_10775Not AvailableNegative2160493 - 216130530465.9
putative penicillin-binding protein pbpxD8875_10780Not AvailableNegative2161541 - 216332266456.8
putative penicillin-binding protein pbpxD8875_10785Not AvailableNegative2163387 - 216517766731.5
hypothetical proteinD8875_10790Not AvailableNegative2165291 - 21654827014.59
maltose/maltodextrin-binding protein precursorD8875_10795Not AvailablePositive2165668 - 216692445112.6
maltose transport system permease protein malfD8875_10800Not AvailablePositive2167005 - 216836350019.2

Displaying genes 2151 – 2160 of 9485 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Infective endocarditisCausesPMC4862721
IeCausesPMC4862721
Bacterial endocarditisCausesPMC4862721
EndocarditisCausesPMC4862721
Infective endocarditisCausesPMC5288394
MeningitisCausesPMC5288394
BacteremiaCausesPMC5288394
Infective endocarditisCausesPMC6060398
EndocarditisCausesPMC6060398
Infective endocarditisCausesPMC3178606

Displaying health effects 1 – 10 of 12 in total