Streptococcus sanguinis

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus sanguinis is a Gram-positive, non-motile coccus that typically forms chains and pairs. This facultative anaerobe thrives in mesophilic temperatures, indicating its adaptation to a moderate temperature range. S. sanguinis is a nonsporulating organism, possessing a single cellular membrane. This species is primarily associated with human hosts and exhibits a free-living biotic relationship. It has been identified with four distinct replicons, which are reflected in its genomic data accessed from multiple sources. The presence of these replicons may contribute to its genetic diversity and adaptability within its ecological niche. Although not characterized as a primary pathogen, S. sanguinis can play a role in human health and disease, particularly in relation to oral microbiota and its potential implications in dental and systemic conditions. The ability of S. sanguinis to exist in both free-living and host-associated states may facilitate its survival and ecological success in varying environments. This duality underscores its importance in both health and disease contexts, as it can contribute to the complex interactions within the human microbiome.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus sanguinis
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus sanguinis
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Oryctolagus cuniculus
Cell arrangementChains - Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus sanguinis strain NCTC11085 chromosome 1, complete

Gene Summary

Adenine Count

698178 bp

Thymine Count

699130 bp

Guanine Count

528176 bp

Cytosine Count

524043 bp

Genome Length

2449527 bp

Protein-coding Genes

2330 genes

Non-Coding Genes

75 genes

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinD8875_00005Not AvailablePositive170 - 52613791.8
glycine betaine/carnitine/choline transport atp-binding protein opucaD8875_00010Not AvailableNegative723 - 148128133.2
inner membrane abc transporter permease protein yjffD8875_00015Not AvailableNegative1478 - 234430151.2
beta-carbonic anhydrase 1D8875_00020Not AvailableNegative2442 - 293918285.8
putative n-acetyltransferase ysneD8875_00025Not AvailableNegative3103 - 358818763.7
hypothetical proteinD8875_00030Not AvailableNegative3745 - 444024945.6
hypothetical proteinD8875_00035Not AvailableNegative4554 - 527025804.5
hypothetical proteinD8875_00040Not AvailableNegative5386 - 657943276.4
histidine phosphatase superfamily (branch 1)D8875_00045Not AvailableNegative6760 - 727519607.4
isochorismatase family proteinD8875_00050Not AvailableNegative7294 - 775217014.3

Displaying genes 1 – 10 of 9485 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Infective endocarditisCausesPMC4862721
IeCausesPMC4862721
Bacterial endocarditisCausesPMC4862721
EndocarditisCausesPMC4862721
Infective endocarditisCausesPMC5288394
MeningitisCausesPMC5288394
BacteremiaCausesPMC5288394
Infective endocarditisCausesPMC6060398
EndocarditisCausesPMC6060398
Infective endocarditisCausesPMC3178606

Displaying health effects 1 – 10 of 12 in total