Streptococcus sanguinis

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus sanguinis is a Gram-positive, non-motile coccus that typically forms chains and pairs. This facultative anaerobe thrives in mesophilic temperatures, indicating its adaptation to a moderate temperature range. S. sanguinis is a nonsporulating organism, possessing a single cellular membrane. This species is primarily associated with human hosts and exhibits a free-living biotic relationship. It has been identified with four distinct replicons, which are reflected in its genomic data accessed from multiple sources. The presence of these replicons may contribute to its genetic diversity and adaptability within its ecological niche. Although not characterized as a primary pathogen, S. sanguinis can play a role in human health and disease, particularly in relation to oral microbiota and its potential implications in dental and systemic conditions. The ability of S. sanguinis to exist in both free-living and host-associated states may facilitate its survival and ecological success in varying environments. This duality underscores its importance in both health and disease contexts, as it can contribute to the complex interactions within the human microbiome.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus sanguinis
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus sanguinis
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Oryctolagus cuniculus
Cell arrangementChains - Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus sanguinis strain BCC64 D8875_contig083, whole genome

Gene Summary

Adenine Count

668774 bp

Thymine Count

673657 bp

Guanine Count

502311 bp

Cytosine Count

519568 bp

Genome Length

2370463 bp

Protein-coding Genes

2283 genes

Non-Coding Genes

51 genes

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
high-affinity branched-chain amino acid transport system permease protein livhD8875_08755Not AvailableNegative1763293 - 176423733572.6
leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein precursorD8875_08760Not AvailableNegative1764484 - 176564440863.9
hypothetical proteinD8875_08765Not AvailableNegative1765733 - 176600210853.0
atp-dependent clp protease proteolytic subunitD8875_08770Not AvailableNegative1766161 - 176675121554.8
uracil phosphoribosyltransferaseD8875_08775Not AvailableNegative1766859 - 176748822765.0
magnesium-transporting atpase, p-type 1D8875_08780Not AvailableNegative1767586 - 177024698449.1
putative gst-like protein yibfD8875_08785Not AvailableNegative1770404 - 177101523784.1
cystathionine beta-lyase patbD8875_08790Not AvailableNegative1771396 - 177256244584.9
cystathionine gamma-synthase/o-acetylhomoserine (thiol)-lyaseD8875_08795Not AvailableNegative1772564 - 177372142345.2
putative cell division protein ytgpD8875_08800Not AvailableNegative1773818 - 177544660053.6

Displaying genes 1751 – 1760 of 9485 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Infective endocarditisCausesPMC4862721
IeCausesPMC4862721
Bacterial endocarditisCausesPMC4862721
EndocarditisCausesPMC4862721
Infective endocarditisCausesPMC5288394
MeningitisCausesPMC5288394
BacteremiaCausesPMC5288394
Infective endocarditisCausesPMC6060398
EndocarditisCausesPMC6060398
Infective endocarditisCausesPMC3178606

Displaying health effects 1 – 10 of 12 in total