Staphylococcus epidermidis

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Caryophanales

Family

Staphylococcaceae

Genus

Staphylococcus

Description

Staphylococcus epidermidis is a Gram-positive, cocci-shaped bacterium that typically arranges itself in clusters or singles. This microbe is non-motile and possesses a single cellular membrane. As a facultative anaerobe, S. epidermidis can grow in both aerobic and anaerobic conditions, with an optimal growth temperature of 30°C, classifying it as mesophilic. S. epidermidis is primarily associated with host environments, reflecting its role as a free-living organism within biological systems. This species is notable for its genetic complexity, possessing three replicons, and its genome is accessible through multiple accession numbers, including NZ_CP040865.1, NZ_CP040870.1, and NZ_CP040869.1. The ability of S. epidermidis to thrive in host-associated habitats suggests its potential involvement in various ecological interactions, particularly within the human microbiome. While S. epidermidis is often regarded as a commensal organism, its presence in host environments underscores the dynamic relationships between microbial communities and their hosts. This characteristic may contribute to its adaptability and resilience in fluctuating conditions, indicating a significant role in maintaining microbial homeostasis.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderCaryophanales
FamilyStaphylococcaceae
GenusStaphylococcus
SpeciesStaphylococcus epidermidis
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Staphylococcus epidermidis
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Bos taurus, Ovis aries
Cell arrangementClusters - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Staphylococcus epidermidis strain HD33 plasmid pHD33_1.

Gene Summary

Adenine Count

1553 bp

Thymine Count

1242 bp

Guanine Count

669 bp

Cytosine Count

452 bp

Genome Length

3916 bp

Protein-coding Genes

3 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dde-type integrase/transposase/recombinaseFH488_RS12535Not AvailablePositive95 - 45413875.1
winged helix-turn-helix transcriptional regulatorFH488_RS12540Not AvailableNegative619 - 95113132.3
6-phospho-3-hexuloisomeraseFH488_RS12545Not AvailableNegative1041 - 158919660.2
3-hexulose-6-phosphate synthaseFH488_RS12550Not AvailableNegative1592 - 222422480.9
glucose-6-phosphate isomeraseFH488_RS12555Not AvailablePositive2425 - 375649698.8
nadp-dependent phosphogluconate dehydrogenaseFH488_RS12560Not AvailablePositive3788 - 519452194.7
glucose-6-phosphate dehydrogenaseFH488_RS12565Not AvailablePositive5258 - 671856886.9
nad(p)h-dependent oxidoreductaseFH488_RS12570Not AvailablePositive6757 - 739524437.3
type i toxin-antitoxin system fst family toxinFH488_RS12575Not AvailableNegative8154 - 82553728.7
hypothetical proteinFH488_RS12815Not AvailableNegative8489 - 86476105.64

Displaying genes 1 – 10 of 21 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

32 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm00027107,8-dihydrofolateC19H19N7O6Chemical structure of 7,8-dihydrofolateNot available
Average441.405Da
Monoisotopic441.1407785Da
BASm0003389NADP(+)C21H25N7O17P3Chemical structure of NADP(+)Not available
Average740.386Da
Monoisotopic740.053624107Da
BASm0014039L-Lactic acidC3H6O3Chemical structure of L-Lactic acid79-33-4
Average90.0779Da
Monoisotopic90.031694058Da
BASm0017265Uridine diphosphate-N-acetylglucosamineC17H27N3O17P2Chemical structure of Uridine diphosphate-N-acetylglucosamine528-04-1
Average607.3537Da
Monoisotopic607.081569477Da
BASm0034737(6S)-5,6,7,8-tetrahydrofolic acidC19H23N7O6Chemical structure of (6S)-5,6,7,8-tetrahydrofolic acidNULL
Average445.4292Da
Monoisotopic445.170981503Da
BASm0039655Achromobacter xylosoxidans A8Not availableNot availableNot available
BASm0039676Clostridium nexileNot availableNot availableNot available

Displaying 1–10 of 32 metabolites

Health Effects

Health ConditionRelationReference
PyelonephritisCausesPMC4308012
Prosthetic valve endocarditisCausesPMC4308012
Central venous catheter infectionsCausesPMC4308012
Cerebrospinal fluid shunt meningitisCausesPMC4308012
UtiCausesPMC4308012
Late-onset sepsisCausesPMC4601917
Infections of implanted cardiac devicesCausesPMC6060398
Acute bacterial meningitisCausesPMC6306750
Bloodstream infectionsCausesPMC8471643
PeritonitisCausesPMC7747055

Displaying health effects 1 – 10 of 11 in total