Aggregatibacter aphrophilus

Gram-negativeRodNon-motileFacultative

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Pasteurellales

Family

Pasteurellaceae

Genus

Aggregatibacter

Description

Aggregatibacter aphrophilus is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic and mesophilic, thriving in moderate temperature ranges. It possesses a unique cellular structure characterized by two membranes and a single replicon in its genome, with accessions demonstrating its genetic composition (QEQC00000000.1). Notably, this microbe lacks motility, and while it possesses flagella, these structures do not facilitate movement. A. aphrophilus is primarily host-associated, indicating its presence in or on living organisms, and it is classified as free-living within its ecological niche. The bacterium exhibits pathogenicity in humans, although specific pathogenic mechanisms are not outlined in the available data. The combination of its environmental adaptability, cellular features, and association with hosts suggests that A. aphrophilus may play a significant role in the microbiota of specific hosts, potentially influencing host health and disease dynamics. The understanding of its interactions within host systems could provide insights into its biological significance and ecological roles.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderPasteurellales
FamilyPasteurellaceae
GenusAggregatibacter
SpeciesAggregatibacter aphrophilus
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Aggregatibacter aphrophilus
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Canis lupus familiaris
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Aggregatibacter aphrophilus strain C2010020251

Gene Summary

Adenine Count

701244 bp

Thymine Count

707282 bp

Guanine Count

524633 bp

Cytosine Count

517314 bp

Genome Length

2450473 bp

Protein-coding Genes

2156 genes

Non-Coding Genes

180 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
HelicaseDPV99_03845Not AvailableNegative833218 - 83459450254.7
Hypothetical proteinDPV99_03850Not AvailableNegative834591 - 83552635496.2
Hypothetical proteinDPV99_03855Not AvailableNegative835683 - 8359138672.47
Hypothetical proteinDPV99_03860Not AvailableNegative835956 - 83639916246.7
Putative transcriptional regulatorDPV99_03865Not AvailableNegative836448 - 8366818783.55
C2DPV99_03870Not AvailablePositive836809 - 83756128332.8
Hypothetical proteinDPV99_03875Not AvailablePositive837586 - 83847034484.4
Hypothetical proteinDPV99_03880Not AvailablePositive838483 - 83891716588.8
hypothetical proteinDPV99_03885Not AvailablePositive839208 - 8394057587.03
Hypothetical proteinDPV99_03890Not AvailablePositive840582 - 84086010309.2

Displaying genes 41 – 50 of 2336 in total

Pathways

22 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

85 records
Metabolite IDMetabolite nameStructureCAS number
BASm00055001-octadecanoyl-sn-glycero-3-phosphateC21H41O7PChemical structure of 1-octadecanoyl-sn-glycero-3-phosphateNot available
Average436.5198Da
Monoisotopic436.2589902Da
BASm0014033AmmoniaH3NChemical structure of Ammonia7664-41-7
Average17.0305Da
Monoisotopic17.026549101Da
BASm0014041Oleic acidC18H34O2Chemical structure of Oleic acid112-80-1
Average282.4614Da
Monoisotopic282.255880332Da
BASm0014058Myristic acidC14H28O2Chemical structure of Myristic acid544-63-8
Average228.3709Da
Monoisotopic228.20893014Da
BASm0014182Vaccenic acidC18H34O2Chemical structure of Vaccenic acidNULL
Average282.468Da
Monoisotopic282.255880335Da
BASm0014219Palmitoleic acidC16H30O2Chemical structure of Palmitoleic acidNULL
Average254.4082Da
Monoisotopic254.224580204Da
BASm0014222DiethanolamineC4H11NO2Chemical structure of DiethanolamineNULL
Average105.1356Da
Monoisotopic105.078978601Da
BASm0017263NADPC21H29N7O17P3Chemical structure of NADP53-59-8
Average744.4129Da
Monoisotopic744.083277073Da
BASm0017395CDP-DG(16:0/18:1(9Z))C46H83N3O15P2Chemical structure of CDP-DG(16:0/18:1(9Z))NULL
Average980.124Da
Monoisotopic979.529942981Da
BASm0017399CDP-DG(18:0/18:1(9Z))C48H87N3O15P2Chemical structure of CDP-DG(18:0/18:1(9Z))NULL
Average1008.178Da
Monoisotopic1007.561243109Da

Displaying 1–10 of 85 metabolites

Health Effects

Health ConditionRelationReference
Culture-negative endocarditisCausesPMC12120218
Valvular infectionCausesPMC12120218
Sphenoid sinusitisCausesPMC12120218
Brain abscessCausesPMC12120218
MeningitisCausesPMC12120218
VentriculitisCausesPMC12120218
Epidural abscessesCausesPMC12120218
Orbital cellulitisCausesPMC12120218
CvstCausesPMC12120218
SovtCausesPMC12120218

Displaying health effects 1 – 10 of 20 in total