Haemophilus influenzae

Gram-negativeRodNon-motileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Pasteurellales

Family

Pasteurellaceae

Genus

Haemophilus

Description

Haemophilus influenzae is a Gram-negative, non-motile rod-shaped bacterium that typically exists in a host-associated habitat, exhibiting a facultative anaerobic oxygen requirement. This mesophilic organism thrives optimally at a temperature of 35°C. It is characterized by having two cellular membranes and possesses flagella, which may play a role in its biological interactions, despite its non-motile nature. Genetically, H. influenzae is notable for its multiple replicons, totaling six, which may contribute to its adaptability and survival in various environments. The organism is classified as free-living within its host-associated habitat, indicating it can exist independently while still being reliant on the host for certain nutrients or environmental conditions. The presence of multiple genome accessions, including NEBH00000000.1 and MZJQ00000000.1, suggests a genetic diversity that may facilitate its persistence and adaptability in host environments. Understanding the ecological role of Haemophilus influenzae provides insight into its interactions within microbial communities, particularly regarding its potential to influence host microbiomes and its contributions to microbial diversity in host-associated environments.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderPasteurellales
FamilyPasteurellaceae
GenusHaemophilus
SpeciesHaemophilus influenzae
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Haemophilus influenzae
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Haemophilus influenzae strain NCTC11426 chromosome 1, complete

Gene Summary

Adenine Count

567396 bp

Thymine Count

568827 bp

Guanine Count

351039 bp

Cytosine Count

347222 bp

Genome Length

1834484 bp

Protein-coding Genes

1666 genes

Non-Coding Genes

124 genes

# of Chromosomes/Plasmids

6

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive585854 - 585866Not Available
Phage major capsid proteinDQL19_RS03000Not AvailablePositive586191 - 58737844024.2
Head maturation proteaseDQL19_RS03005Not AvailablePositive587432 - 58799820953.7
Portal proteinDQL19_RS03010Not AvailablePositive588000 - 58923246187.6
Putative head-tail adaptorDQL19_RS03015Not AvailablePositive589216 - 58956012812.5
Head-tail connector proteinDQL19_RS03020Not AvailablePositive589547 - 58986111865.2
Hypothetical proteinDQL19_RS03025Not AvailablePositive589876 - 59026214752.6
Terminase small subunitDQL19_RS03030Not AvailablePositive590459 - 59082713751.5
Terminase large subunitDQL19_RS03035Not AvailablePositive590834 - 59250163196.1
hypothetical proteinDQL19_RS03040Not AvailablePositive592498 - 59278210994.3

Displaying genes 1 – 10 of 11180 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Ear infection (otitis media)CausesPMC10964412
Lung infection (pneumonia)CausesPMC10964412
Exacerbations of chronic pulmonary diseases (e.g., chronic obstructive pulmonary disease, protracted bacterial bronchitis, and bronchiectasis)CausesPMC10964412
Ear infectionCausesPMC10964412
Otitis mediaCausesPMC10964412
Lung infectionCausesPMC10964412
PneumoniaCausesPMC10964412
Invasive diseaseCausesPMC10964412
MeningitisCausesPMC11116026
EncephalitisCausesPMC11116026

Displaying health effects 1 – 10 of 60 in total