Escherichia coli ISC56

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Escherichia coli ISC56 is a Gram-negative, rod-shaped bacterium that exhibits a versatile cell arrangement, existing as singles, pairs, or in chains. This strain is categorized as a nonsporulating organism, which suggests an adaptation to environments where sporulation is not necessary for survival. E. coli ISC56 is a facultative anaerobe, indicating its ability to thrive in both aerobic and anaerobic conditions, and it is a chemoheterotroph, relying on organic compounds for energy and carbon sources. The optimal growth temperature for E. coli ISC56 is 37.0 °C, which aligns with the typical physiological temperature of warm-blooded hosts, suggesting its adaptation to a host-associated habitat. This characteristic reinforces the notion that E. coli ISC56 is likely well-suited for life within the gastrointestinal tract of mammals, where it may play a role in nutrient processing and microbial community dynamics. In summary, the combination of its Gram-negative status, rod shape, and facultative anaerobic metabolism positions E. coli ISC56 as a significant microbe within host-associated environments, potentially contributing to the complex interactions within the microbiota. This underscores the importance of understanding such strains in the context of their ecological roles and their influence on host health and microbial ecology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli ISC56
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipSymbiotic
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain ISC56 genome assembly, contig: c685,

Gene Summary

Adenine Count

1203979 bp

Thymine Count

1205563 bp

Guanine Count

1572452 bp

Cytosine Count

1569193 bp

Genome Length

5551285 bp

Protein-coding Genes

5704 genes

Non-Coding Genes

244 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Terminase small subunitNONENot AvailablePositive525807 - 52640922355.6
Terminase large subunitNONENot AvailablePositive526409 - 52788156525.9
Portal proteinNONENot AvailablePositive527894 - 52931552281.6
Phage head morphogenesisNONENot AvailablePositive529290 - 53029437662.4
hypothetical proteinNONENot AvailablePositive530408 - 53081215326.9
Hypothetical proteinNONENot AvailablePositive530885 - 53227050960.0
Capsid proteinNONENot AvailablePositive532274 - 53270215246.3
Capsid proteinNONENot AvailablePositive532714 - 53380840914.2
Hypothetical proteinNONENot AvailablePositive533819 - 5340588342.72
Hypothetical proteinNONENot AvailablePositive534061 - 53444113010.7

Displaying genes 1 – 10 of 5948 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total