Escherichia coli O157:H7

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli O157:H7 is a Gram-negative, rod-shaped bacterium that typically appears in pairs or as single cells. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. E. coli O157:H7 has an optimal temperature of approximately 37.0°C, which coincides with the average human body temperature, suggesting a significant association with warm-blooded hosts. The habitat of E. coli O157:H7 is primarily host-associated, indicating a strong relationship with the gastrointestinal tracts of animals, particularly ruminants such as cattle. This association highlights the bacterium's potential for transmission through the food chain, particularly in undercooked or contaminated food products. Furthermore, the facultative anaerobic nature of E. coli O157:H7 may confer advantages in fluctuating oxygen conditions within the gut environment, allowing it to maintain metabolic versatility. Unique to E. coli O157:H7 is its adaptation to thrive in host-associated niches, which not only facilitates its survival but may also influence its interactions with the host microbiome. This interplay could have implications for both microbial community dynamics and host health, underscoring the importance of understanding this pathogen's role in the broader ecological context of gut microbiota.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
StrainO157:H7

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli O157:H7
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli O157:H7 strain FWSEC0004 plasmid unnamed13,

Gene Summary

Adenine Count

24897 bp

Thymine Count

23755 bp

Guanine Count

23849 bp

Cytosine Count

20253 bp

Genome Length

92754 bp

Protein-coding Genes

97 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Transcriptional regulatorAU473_RS12725Not AvailablePositive2509134 - 250944812085.7
Hypothetical proteinAU473_RS29815Not AvailableNegative2509530 - 25097548709.32
Gp1AU473_RS12730Not AvailablePositive2510149 - 251065819171.9
Dna packaging proteinAU473_RS12735Not AvailablePositive2510630 - 251255872699.6
Head-tail connector gpwAU473_RS12740Not AvailablePositive2512542 - 25127487674.37
Bacteriophage portal proteinAU473_RS12745Not AvailablePositive2512745 - 251433759652.5
Bacteriophage prohead proteaseAU473_RS12750Not AvailablePositive2514327 - 251583252329.9
Bacteriophage head decoration proteinAU473_RS12755Not AvailablePositive2515869 - 251621611997.2
Bacteriophage major capsid proteinAU473_RS12760Not AvailablePositive2516274 - 25165259768.06
Major tail protein vAU473_RS12765Not AvailablePositive2516522 - 251726225930.2

Displaying genes 381 – 390 of 11382 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total