Escherichia coli O157:H7

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli O157:H7 is a Gram-negative, rod-shaped bacterium that typically appears in pairs or as single cells. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. E. coli O157:H7 has an optimal temperature of approximately 37.0°C, which coincides with the average human body temperature, suggesting a significant association with warm-blooded hosts. The habitat of E. coli O157:H7 is primarily host-associated, indicating a strong relationship with the gastrointestinal tracts of animals, particularly ruminants such as cattle. This association highlights the bacterium's potential for transmission through the food chain, particularly in undercooked or contaminated food products. Furthermore, the facultative anaerobic nature of E. coli O157:H7 may confer advantages in fluctuating oxygen conditions within the gut environment, allowing it to maintain metabolic versatility. Unique to E. coli O157:H7 is its adaptation to thrive in host-associated niches, which not only facilitates its survival but may also influence its interactions with the host microbiome. This interplay could have implications for both microbial community dynamics and host health, underscoring the importance of understanding this pathogen's role in the broader ecological context of gut microbiota.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
StrainO157:H7

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli O157:H7
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli O157:H7 strain FWSEC0004 plasmid unnamed13,

Gene Summary

Adenine Count

24897 bp

Thymine Count

23755 bp

Guanine Count

23849 bp

Cytosine Count

20253 bp

Genome Length

92754 bp

Protein-coding Genes

97 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Putative ninh proteinAU473_RS11535Not AvailablePositive2274246 - 22744407266.74
Hypothetical proteinAU473_RS11540Not AvailablePositive2274433 - 227486616264.7
Shiga toxin 1 subunit aAU473_RS11545Not AvailablePositive2275373 - 227632034815.8
Shiga toxin 1 subunit bAU473_RS11550Not AvailablePositive2276330 - 22765999743.67
Hypothetical proteinAU473_RS11555Not AvailablePositive2277110 - 227905668779.7
Hypothetical proteinAU473_RS11560Not AvailablePositive2279194 - 22793736804.38
Hypothetical proteinAU473_RS11565Not AvailablePositive2279414 - 22796598564.03
Holin proteinAU473_RS11570Not AvailablePositive2279737 - 22799528026.76
EndolysinAU473_RS11575Not AvailablePositive2279957 - 228049019608.5
Antirepressor proteinAU473_RS11580Not AvailablePositive2280761 - 228133021432.3

Displaying genes 301 – 310 of 11382 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total