Escherichia coli str. SLK172

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain SLK172 is a Gram-negative, rod-shaped bacterium that commonly exists in a host-associated habitat. This strain exhibits a cellular arrangement primarily in pairs and singles, reflecting its typical morphology within diverse environments. E. coli SLK172 thrives optimally at a temperature of 37.0°C, which aligns with the physiological conditions found in the intestines of warm-blooded hosts. As a facultative anaerobe, E. coli SLK172 possesses the metabolic flexibility to grow in both the presence and absence of oxygen, enabling it to adapt to varying oxygen levels within its host environment. This adaptability is crucial for survival in the dynamic conditions of the gastrointestinal tract, where oxygen availability can fluctuate significantly due to microbial activity and host physiology. The association of E. coli SLK172 with host organisms suggests potential roles in nutrient metabolism and microbial community dynamics within the gut ecosystem. Understanding the specific interactions of this strain with its host could provide insights into its contributions to health and disease, as well as its potential influence on the overall gut microbiome. Such knowledge may further illuminate the ecological significance of E. coli strains in maintaining gut homeostasis and their responses to environmental changes.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
StrainSLK172

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli str. SLK172
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain SLK172 plasmid pSLK172-1, complete

Gene Summary

Adenine Count

96769 bp

Thymine Count

97487 bp

Guanine Count

86667 bp

Cytosine Count

88375 bp

Genome Length

369298 bp

Protein-coding Genes

289 genes

Non-Coding Genes

108 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
is6-like element is26 family transposaseBJJ90_RS30895Not AvailablePositive1 - 70527953.9
extended-spectrum class a beta-lactamase ctx-m-55BJJ90_RS30910Not AvailablePositive1127 - 200231173.4
wbuc family cupin fold metalloproteinBJJ90_RS30915Not AvailableNegative2049 - 252517478.8
is1 family transposaseBJJ90_RS30920Not AvailableNegative2784 - 352727147.6
is6-like element is26 family transposaseBJJ90_RS30925Not AvailableNegative3577 - 428127896.9
fosfomycin resistance glutathione transferase fosa3BJJ90_RS30935Not AvailablePositive4667 - 508315402.2
fidl-like proteinBJJ90_RS30940Not AvailableNegative5088 - 560619343.1
transcriptional regulatorBJJ90_RS30945Not AvailableNegative5606 - 639429670.1
is1 family transposaseBJJ90_RS30950Not AvailableNegative6414 - 683915908.3
is6-like element is26 family transposaseBJJ90_RS30960Not AvailableNegative6894 - 759827896.9

Displaying genes 1 – 10 of 547 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total