Escherichia coli str. MS8345

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli str. MS8345 is a Gram-negative, rod-shaped bacterium that typically exists in pairs or as singles. This strain thrives optimally at a temperature of 37.0°C, which aligns with the typical body temperature of warm-blooded hosts, indicating its adaptation to a host-associated habitat. E. coli str. MS8345 is categorized as a facultative anaerobe, allowing it to grow in both aerobic and anaerobic environments, a trait that enhances its survival and colonization potential within diverse host conditions. The facultative anaerobic nature of this strain may enable it to effectively utilize available metabolic pathways depending on the oxygen levels present in its environment, which is particularly advantageous in the fluctuating conditions found within host organisms. The ability to persist in varying oxygen concentrations could also contribute to its resilience in different biological niches, potentially influencing its interactions with the host's microbiome. Overall, the combination of its optimal growth temperature, rod shape, and versatile metabolic capabilities underscores the adaptability of E. coli str. MS8345 within host-associated environments, highlighting its role in the complex interplay of microbial communities within the host ecosystem. Understanding these traits may provide insights into its functional roles and contributions to host health and microbial dynamics.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
StrainMS8345

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli str. MS8345
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain MS8345 plasmid pMS8345A, complete

Gene Summary

Adenine Count

64480 bp

Thymine Count

65049 bp

Guanine Count

55157 bp

Cytosine Count

56476 bp

Genome Length

241162 bp

Protein-coding Genes

240 genes

Non-Coding Genes

26 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
tyrosine-type recombinase/integraseMS8345_RS28805Not AvailablePositive132 - 87228192.5
repb family plasmid replication initiator proteinMS8345_RS28810Not AvailableNegative1157 - 213437317.0
integrase core domain-containing proteinMS8345_RS28820Not AvailablePositive2880 - 320312961.1
integrase core domain-containing proteinMS8345_RS30200Not AvailablePositive3205 - 33093832.48
integrase core domain-containing proteinMS8345_RS28830Not AvailablePositive3370 - 388317986.5
is1-like element is1a family transposaseMS8345_RS28835Not AvailableNegative4063 - 476026483.3
iron/manganese abc transporter substrate-binding protein sitaMS8345_RS28850Not AvailablePositive5116 - 603033424.1
iron/manganese abc transporter atp-binding protein sitbMS8345_RS28855Not AvailablePositive6030 - 685730104.5
iron/manganese abc transporter permease subunit sitcMS8345_RS28860Not AvailablePositive6854 - 771130762.6
iron/manganese abc transporter permease subunit sitdMS8345_RS28865Not AvailablePositive7708 - 856530727.9

Displaying genes 1 – 10 of 404 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total