Helicobacter pylori str. 1786/05

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. 1786/05 is a microaerophilic, Gram-negative bacterium characterized by its spirilla shape and presence as single cells. This strain has an optimal growth temperature of 37.0°C, aligning with the typical physiological conditions found within the gastric environment of its host. H. pylori is predominantly host-associated, commonly residing in the human stomach, where it is adapted to thrive in low-oxygen environments. The microaerophilic nature of this bacterium suggests a specialized metabolic capability that allows it to utilize oxygen at reduced concentrations, which is critical for its survival and colonization in the gastric mucosa. The unique morphological and physiological traits of H. pylori str. 1786/05 may contribute to its ability to establish a niche within the host's stomach, where it interacts with the gastric epithelium. Understanding these traits is crucial for elucidating the ecological roles of H. pylori in the human microbiome and its potential implications for gastrointestinal health. The microbe's adaptation to microaerophilic conditions highlights the intricate relationship between this bacterium and its host environment, suggesting a finely tuned balance that may influence both microbial community dynamics and host pathophysiology.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain1786/05

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 1786/05
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 1786/05 plasmid pHPY1786, whole genome

Gene Summary

Adenine Count

3240 bp

Thymine Count

3276 bp

Guanine Count

1760 bp

Cytosine Count

1684 bp

Genome Length

9960 bp

Protein-coding Genes

9 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hydroxyethylthiazole kinaseHPY1786_00285Not AvailablePositive54612 - 5539127556.4
phosphomethylpyrimidine kinaseHPY1786_00290Not AvailablePositive55388 - 5619728824.3
thiamine-phosphate pyrophosphorylaseHPY1786_00295Not AvailablePositive56190 - 5684923920.5
hypothetical proteinHPY1786_00300Not AvailableNegative56858 - 5759527958.4
phosphopantothenate synthaseHPY1786_00305Not AvailableNegative57595 - 5887246786.8
udp-n-acetylglucosamine 4,6-dehydrataseHPY1786_00310Not AvailableNegative58869 - 5985236628.6
membrane proteinHPY1786_00315Not AvailableNegative59874 - 6163763508.1
hypothetical proteinHPY1786_00320Not AvailableNegative61634 - 6225124354.3
lipoproteinHPY1786_00325Not AvailableNegative62271 - 6287621920.8
Trna-argNot AvailableNot AvailablePositive63426 - 63502Not Available

Displaying genes 71 – 80 of 1518 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total