Helicobacter pylori str. 1786/05

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. 1786/05 is a microaerophilic, Gram-negative bacterium characterized by its spirilla shape and presence as single cells. This strain has an optimal growth temperature of 37.0°C, aligning with the typical physiological conditions found within the gastric environment of its host. H. pylori is predominantly host-associated, commonly residing in the human stomach, where it is adapted to thrive in low-oxygen environments. The microaerophilic nature of this bacterium suggests a specialized metabolic capability that allows it to utilize oxygen at reduced concentrations, which is critical for its survival and colonization in the gastric mucosa. The unique morphological and physiological traits of H. pylori str. 1786/05 may contribute to its ability to establish a niche within the host's stomach, where it interacts with the gastric epithelium. Understanding these traits is crucial for elucidating the ecological roles of H. pylori in the human microbiome and its potential implications for gastrointestinal health. The microbe's adaptation to microaerophilic conditions highlights the intricate relationship between this bacterium and its host environment, suggesting a finely tuned balance that may influence both microbial community dynamics and host pathophysiology.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain1786/05

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 1786/05
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 1786/05 Contig41, whole genome shotgun

Gene Summary

Adenine Count

495865 bp

Thymine Count

492997 bp

Guanine Count

317557 bp

Cytosine Count

313234 bp

Genome Length

1619972 bp

Protein-coding Genes

1467 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
thif family adenylyltransferaseHPY1786_RS00005Not AvailableNegative1 - 105339964.9
relaxase/mobilization nuclease domain-containing proteinHPY1786_RS07950Not AvailableNegative1333 - 334879208.0
plasmid mobilization proteinHPY1786_RS00020Not AvailableNegative3338 - 368213276.1
hypothetical proteinHPY1786_RS00025Not AvailablePositive3882 - 416310941.2
type ii toxin-antitoxin system yafq family toxinHPY1786_RS00030Not AvailablePositive4172 - 444110485.1
replication initiation proteinHPY1786_RS00035Not AvailablePositive5447 - 700961398.4
fic family proteinHPY1786_RS00040Not AvailablePositive7054 - 778828146.2
fic family proteinHPY1786_RS00045Not AvailablePositive7838 - 856628271.8
mfs transporterHPY1786_RS00050Not AvailableNegative8786 - 994943868.2
fad-binding proteinHPY1786_00005Not AvailablePositive1 - 114541616.5

Displaying genes 1 – 10 of 1518 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total