Helicobacter pylori str. 3046

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 3046 is a Gram-negative bacterium characterized by its spirilla shape and arrangement as single cells. This microbe thrives optimally at a temperature of 37.0°C, which is consistent with its adaptation to a host-associated habitat, primarily residing in the gastric mucosa of mammals. As a microaerophilic organism, H. pylori strain 3046 requires a reduced level of oxygen for growth, reflecting its specialized niche within the acidic environment of the stomach. The morphology and growth conditions of H. pylori strain 3046 suggest an evolutionary adaptation to its environment, allowing it to colonize the gastric epithelium effectively. Its microaerophilic nature indicates a reliance on specific oxygen concentrations that are typically found in the stomach, further emphasizing its specialized role within the host. Understanding the traits of H. pylori strain 3046 contributes to a broader comprehension of the survival strategies employed by microbes in complex host-associated ecosystems. This strain exemplifies how specific adaptations can influence microbial behavior and interactions within the gastrointestinal tract, potentially affecting host health and disease dynamics.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain3046

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 3046
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 3046 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

513166 bp

Thymine Count

513092 bp

Guanine Count

325403 bp

Cytosine Count

326223 bp

Genome Length

1677884 bp

Protein-coding Genes

1493 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
guanylate kinaseBB454_02005Not AvailableNegative806465 - 80708523859.8
hypothetical proteinBB454_02010Not AvailableNegative807078 - 80863459948.6
nuclease nuctBB454_02015Not AvailablePositive808779 - 80932120185.6
hypothetical proteinBB454_02020Not AvailableNegative809329 - 81004827088.1
flagellar basal body l-ring proteinBB454_02025Not AvailablePositive810213 - 81092626467.2
pseudaminic acid cytidylyltransferaseBB454_02030Not AvailablePositive810944 - 81162725894.2
cmp-n-acetylneuraminic acid synthetaseBB454_02035Not AvailablePositive811618 - 81249033236.3
udp-4-amino-4, 6-dideoxy-n-acetyl-beta-l-altrosamine n-acetyltransferaseBB454_02040Not AvailablePositive812487 - 81302921312.8
tetraacyldisaccharide 4'-kinaseBB454_02045Not AvailableNegative812962 - 81390035547.6
nad(+) synthetaseBB454_02050Not AvailableNegative813887 - 81467829635.9

Displaying genes 721 – 730 of 1535 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total