Helicobacter pylori str. 3046

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 3046 is a Gram-negative bacterium characterized by its spirilla shape and arrangement as single cells. This microbe thrives optimally at a temperature of 37.0°C, which is consistent with its adaptation to a host-associated habitat, primarily residing in the gastric mucosa of mammals. As a microaerophilic organism, H. pylori strain 3046 requires a reduced level of oxygen for growth, reflecting its specialized niche within the acidic environment of the stomach. The morphology and growth conditions of H. pylori strain 3046 suggest an evolutionary adaptation to its environment, allowing it to colonize the gastric epithelium effectively. Its microaerophilic nature indicates a reliance on specific oxygen concentrations that are typically found in the stomach, further emphasizing its specialized role within the host. Understanding the traits of H. pylori strain 3046 contributes to a broader comprehension of the survival strategies employed by microbes in complex host-associated ecosystems. This strain exemplifies how specific adaptations can influence microbial behavior and interactions within the gastrointestinal tract, potentially affecting host health and disease dynamics.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain3046

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 3046
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 3046 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

513166 bp

Thymine Count

513092 bp

Guanine Count

325403 bp

Cytosine Count

326223 bp

Genome Length

1677884 bp

Protein-coding Genes

1493 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinBB454_00005Not AvailableNegative123 - 3327694.17
1-pyrroline-5-carboxylate dehydrogenaseBB454_00010Not AvailablePositive682 - 4239135043.0
23s ribosomal rnaNot AvailableNot AvailablePositive1078 - 3966Not Available
5s ribosomal rnaNot AvailableNot AvailablePositive4203 - 4320Not Available
sodium/proline symporterBB454_00015Not AvailablePositive4266 - 575654124.3
dna (cytosine-5-)-methyltransferaseBB454_00020Not AvailablePositive5796 - 708248894.4
dna methyltransferaseBB454_00025Not AvailablePositive7079 - 777126911.8
agmatine deiminaseBB454_00030Not AvailablePositive7830 - 882237486.1
carbamoyltransferase hypfBB454_00035Not AvailablePositive8819 - 1107185188.2
hydrogenase expression/formation protein hypeBB454_00040Not AvailablePositive11074 - 1207236345.4

Displaying genes 1 – 10 of 1535 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total