Helicobacter pylori str. 173/00

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 173/00 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This organism thrives optimally at 37.0°C, which aligns with the average human body temperature, suggesting an adaptation to a host-associated habitat. H. pylori is predominantly found in the gastric mucosa of humans, where it establishes a niche that may influence gastric health and disease. The microaerophilic nature of H. pylori indicates that it requires reduced levels of oxygen for growth, which is consistent with its colonization of the stomach's acidic environment, where oxygen availability is limited. This trait likely contributes to its survival and persistence in the gastric niche, as well as its ability to evade the host's immune responses. An intriguing aspect of H. pylori strain 173/00 is its potential role in the complex interplay between the host and its microbiota, particularly in relation to gastric diseases. Understanding the specific interactions of this strain within the digestive ecosystem may provide insights into its ecological significance and its contribution to overall gastrointestinal health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain173/00

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 173/00
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 173/00 Contig79, whole genome shotgun

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1438 genes

Non-Coding Genes

41 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
membrane proteinHPY173_00135Not AvailablePositive26308 - 2700326272.3
branched-chain amino acid aminotransferaseHPY173_00140Not AvailableNegative27008 - 2803037581.3
membrane proteinHPY173_00145Not AvailableNegative28081 - 2882728053.6
dna polymerase iHPY173_00150Not AvailableNegative28942 - 31599101006.0
restriction endonuclease subunit rHPY173_00155Not AvailableNegative31666 - 3220820441.5
restriction endonuclease subunit sHPY173_00160Not AvailableNegative32235 - 3287023697.6
restriction endonuclease subunit mHPY173_00165Not AvailableNegative32867 - 3491277241.6
amidophosphoribosyltransferaseHPY173_00170Not AvailableNegative34944 - 3551921369.1
thymidylate kinaseHPY173_00175Not AvailableNegative35507 - 3608221456.4
phosphopantetheine adenylyltransferaseHPY173_00180Not AvailableNegative36084 - 3655717632.5

Displaying genes 31 – 40 of 1483 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total