Helicobacter pylori str. 173/00

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 173/00 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This organism thrives optimally at 37.0°C, which aligns with the average human body temperature, suggesting an adaptation to a host-associated habitat. H. pylori is predominantly found in the gastric mucosa of humans, where it establishes a niche that may influence gastric health and disease. The microaerophilic nature of H. pylori indicates that it requires reduced levels of oxygen for growth, which is consistent with its colonization of the stomach's acidic environment, where oxygen availability is limited. This trait likely contributes to its survival and persistence in the gastric niche, as well as its ability to evade the host's immune responses. An intriguing aspect of H. pylori strain 173/00 is its potential role in the complex interplay between the host and its microbiota, particularly in relation to gastric diseases. Understanding the specific interactions of this strain within the digestive ecosystem may provide insights into its ecological significance and its contribution to overall gastrointestinal health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain173/00

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 173/00
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 173/00 plasmid pHPY173, whole genome

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

4 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
camp-induced filamentation proteinHPY173_00005Not AvailablePositive50 - 75727642.2
23s ribosomal rnaNot AvailableNot AvailablePositive1027 - 3917Not Available
replication a proteinHPY173_00010Not AvailablePositive1799 - 341563877.3
fic family proteinHPY173_00015Not AvailablePositive3460 - 419428083.0
5s ribosomal rnaNot AvailableNot AvailablePositive4149 - 4266Not Available
single-stranded dna-binding proteinHPY173_00020Not AvailablePositive4195 - 447711206.9
biopolymer transporter exbbHPY173_00025Not AvailablePositive4480 - 493216666.0
biopolymer transporter exbdHPY173_00030Not AvailablePositive4943 - 534415042.4
50s ribosomal protein l34HPY173_00035Not AvailablePositive5416 - 55505246.63
ribonuclease pHPY173_00040Not AvailablePositive5510 - 599518739.1

Displaying genes 1 – 10 of 1483 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total