Campylobacter hominis CH001A

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Campylobacteraceae

Genus

Campylobacter

Description

Campylobacter hominis CH001A is a Gram-negative rod-shaped bacterium primarily found in the gut, gut microbiome, and oral cavity of its host, Homo sapiens. This species is characterized by its anaerobic oxygen requirement and is mesophilic, with an optimal growth temperature of 37°C. Campylobacter hominis CH001A exhibits a unique cell arrangement, typically forming chains or existing as single cells. This bacterium possesses flagella, which are indicative of motility; however, it is noted that Campylobacter hominis CH001A does not demonstrate mobility in its ecological niche. It is free-living, suggesting that it can thrive independently in its environment. The health implications of Campylobacter hominis CH001A are significant, as it has been associated with conditions such as gastroenteritis, inflammatory bowel disease (IBD), and Barrett's esophagus. These associations underscore the potential pathogenicity of the species within human hosts. Genetically, Campylobacter hominis CH001A contains three replicons, which may play a role in its adaptability and survival in the gut environment. The presence of this bacterium in the gut microbiome may influence the microbial community dynamics and could have implications for human health, particularly concerning gastrointestinal diseases. Understanding the role of Campylobacter hominis CH001A in the gut microbiome could provide insights into its contributions to both health and disease states in humans.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyCampylobacteraceae
GenusCampylobacter
SpeciesCampylobacter hominis
StrainCH001A

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Campylobacter hominis CH001A
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
Habitatgut; gut microbiome; oral cavity
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Campylobacter hominis CH001A, Complete Genome

Gene Summary

Adenine Count

584060 bp

Thymine Count

584453 bp

Guanine Count

270712 bp

Cytosine Count

272440 bp

Genome Length

1711665 bp

Protein-coding Genes

1606 genes

Non-Coding Genes

70 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
G proteinK8O82_05250Not AvailablePositive1106973 - 110750619591.6
Hypothetical proteinK8O82_05255Not AvailableNegative1107529 - 110829329038.4
hypothetical proteinK8O82_05260Not AvailableNegative1108290 - 110878719477.6
hypothetical proteinK8O82_05265Q72GI8Negative1108868 - 11090567084.68
regulatory protein gemaK8O82_05270Not AvailableNegative1109173 - 110964918738.2
hypothetical proteinK8O82_05275Not AvailableNegative1109660 - 11098698368.38
Host-nuclease inhibitor protein gam2c putativeK8O82_05280Not AvailableNegative1109924 - 111041218725.7
cytochrome-c oxidase, cbb3-type subunit iK8O82_00010D9IA43Positive9042 - 1050855569.8
cytochrome-c oxidase, cbb3-type subunit iiK8O82_00015Not AvailablePositive10520 - 1118824846.9
cytochrome c oxidase, cbb3-type, ccoq subunitK8O82_00020Not AvailablePositive11203 - 114248719.42

Displaying genes 21 – 30 of 1680 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

Health ConditionRelationReference
Inflammatory bowel disease (ibd)CausesPMC8567795
Barrett s oesophagusCausesPMC8567795
GastroenteritisCausesPMC8567795

Displaying health effects 1 – 3 of 3 in total