Campylobacter hominis CH001A

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Campylobacteraceae

Genus

Campylobacter

Description

Campylobacter hominis CH001A is a Gram-negative rod-shaped bacterium primarily found in the gut, gut microbiome, and oral cavity of its host, Homo sapiens. This species is characterized by its anaerobic oxygen requirement and is mesophilic, with an optimal growth temperature of 37°C. Campylobacter hominis CH001A exhibits a unique cell arrangement, typically forming chains or existing as single cells. This bacterium possesses flagella, which are indicative of motility; however, it is noted that Campylobacter hominis CH001A does not demonstrate mobility in its ecological niche. It is free-living, suggesting that it can thrive independently in its environment. The health implications of Campylobacter hominis CH001A are significant, as it has been associated with conditions such as gastroenteritis, inflammatory bowel disease (IBD), and Barrett's esophagus. These associations underscore the potential pathogenicity of the species within human hosts. Genetically, Campylobacter hominis CH001A contains three replicons, which may play a role in its adaptability and survival in the gut environment. The presence of this bacterium in the gut microbiome may influence the microbial community dynamics and could have implications for human health, particularly concerning gastrointestinal diseases. Understanding the role of Campylobacter hominis CH001A in the gut microbiome could provide insights into its contributions to both health and disease states in humans.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyCampylobacteraceae
GenusCampylobacter
SpeciesCampylobacter hominis
StrainCH001A

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Campylobacter hominis CH001A
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
Habitatgut; gut microbiome; oral cavity
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Campylobacter hominis CH001A, Complete Genome

Gene Summary

Adenine Count

584060 bp

Thymine Count

584453 bp

Guanine Count

270712 bp

Cytosine Count

272440 bp

Genome Length

1711665 bp

Protein-coding Genes

1606 genes

Non-Coding Genes

70 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
coproporphyrinogen iii oxidase family proteinK8O82_06310P54304Negative1298755 - 130002948978.4
virulence rhum family proteinK8O82_06315A0RRF8Negative1300035 - 130053318906.6
d-2-hydroxyacid dehydrogenaseK8O82_06320C0CMQ8Negative1300523 - 130145533898.9
iron-sulfur cluster assembly scaffold protein nifuK8O82_06325P05340Negative1302697 - 130368936383.4
nifs family cysteine desulfuraseK8O82_06330Q9ZML2Negative1303703 - 130489343135.6
gtp cyclohydrolase i foleK8O82_06335A7GW42Negative1304965 - 130554922195.2
dna-binding proteinK8O82_06340Not AvailableNegative1305866 - 130648924164.5
30s ribosomal protein s21K8O82_06345A7HZH0Negative1306584 - 13067968632.72
hypothetical proteinK8O82_06350Not AvailableNegative1306861 - 130807245846.7
duf493 domain-containing proteinK8O82_06355O25237Negative1308082 - 130834810154.5

Displaying genes 1261 – 1270 of 1680 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

Health ConditionRelationReference
Inflammatory bowel disease (ibd)CausesPMC8567795
Barrett s oesophagusCausesPMC8567795
GastroenteritisCausesPMC8567795

Displaying health effects 1 – 3 of 3 in total