Clostridium scindens

Rodanaerobic

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Lachnoclostridium

Description

Clostridium scindens is a Gram-positive, anaerobic bacterium characterized by its rod shape and presence of flagella. It is primarily found in the gastrointestinal tract, specifically in the cecum, colon, distal intestine, ileum, and feces of various hosts, including Homo sapiens, Metazoa, and Sus scrofa. This organism typically exists in chains or as singles within its habitat. C. scindens thrives in mesophilic temperature ranges, indicating its preference for moderate temperatures conducive to its growth and activity. It possesses a single replicon, which is a characteristic of its genomic organization. This bacterium plays a significant role in the gut microbiome, contributing to the complex ecosystem of the gastrointestinal tract. Its presence is linked to various metabolic processes, including the fermentation of dietary fibers and the production of short-chain fatty acids, which are beneficial for gut health. The ecological insights provided by the study of C. scindens underscore its importance in maintaining gut homeostasis and its potential implications in human health and disease.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusLachnoclostridium
Species[Clostridium] scindens
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Clostridium scindens
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsanaerobic
Optimal temperatureNot Available
Temperature rangemesophilic
Habitatcecum; colon; distal intestine; feces; GI tract; gut; gut microbiome; ileum; large intestine
Biotic relationshipNot Available
Host(s)Homo sapiens, Metazoa, Sus scrofa
Cell arrangementChains; Chains, Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Clostridium scindens , Complete Genome

Gene Summary

Adenine Count

1027942 bp

Thymine Count

1059284 bp

Guanine Count

939860 bp

Cytosine Count

955966 bp

Genome Length

3983052 bp

Protein-coding Genes

3637 genes

Non-Coding Genes

144 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinGGADHKLB_01484Not AvailableNegative1529695 - 153005713451.0
Tail tape measure proteinGGADHKLB_01485E7DNB6Negative1530057 - 153277195433.8
hypothetical proteinGGADHKLB_01486Not AvailableNegative1532793 - 15329576162.34
Hypothetical proteinGGADHKLB_01487Not AvailableNegative1532954 - 153333114509.3
Major tail proteinGGADHKLB_01488Not AvailableNegative1533344 - 153399723828.4
Putative aminopeptidaseGGADHKLB_01489Not AvailableNegative1534012 - 153432912304.4
Hypothetical proteinGGADHKLB_01490Not AvailableNegative1534332 - 153471514095.7
Head-tail adaptor proteinGGADHKLB_01491Not AvailableNegative1534712 - 153504412305.5
Putative dna packaging proteinGGADHKLB_01492Not AvailableNegative1535044 - 153533111035.1
Phage major capsid proteinGGADHKLB_01493Q6QGD8Negative1535410 - 153661544469.4

Displaying genes 81 – 90 of 3781 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

40 records
Metabolite IDMetabolite nameStructureCAS number
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm00037267alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oateC24H35O5Chemical structure of 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oateNot available
Average403.54Da
Monoisotopic403.2489978Da
BASm000372712alpha-hydroxy-3-oxochola-4,6-dien-24-oateC24H33O4Chemical structure of 12alpha-hydroxy-3-oxochola-4,6-dien-24-oateNot available
Average385.525Da
Monoisotopic385.2384331Da
BASm0003731deoxycholoyl-CoAC45H70N7O19P3SChemical structure of deoxycholoyl-CoANot available
Average1138.07Da
Monoisotopic1137.36819955Da
BASm0004391chenodeoxycholoyl-CoAC45H70N7O19P3SChemical structure of chenodeoxycholoyl-CoANot available
Average1138.07Da
Monoisotopic1137.3682Da
BASm0007624lithocholoyl-CoAC45H70N7O18P3SChemical structure of lithocholoyl-CoANot available
Average1122.07Da
Monoisotopic1121.373285Da
BASm00076867alpha-hydroxy-3-oxochol-4-en-24-oateC24H35O4Chemical structure of 7alpha-hydroxy-3-oxochol-4-en-24-oateNot available
Average387.541Da
Monoisotopic387.254083187Da
BASm00076873-oxochola-4,6-dien-24-oateC24H33O3Chemical structure of 3-oxochola-4,6-dien-24-oateNot available
Average369.526Da
Monoisotopic369.243518503Da
BASm00083127alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oyl-CoAC45H66N7O20P3SChemical structure of 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oyl-CoANot available
Average1150.04Da
Monoisotopic1149.331814041Da
BASm000831312alpha-hydroxy-3-oxochola-4,6-dien-24-oyl-CoAC45H64N7O19P3SChemical structure of 12alpha-hydroxy-3-oxochola-4,6-dien-24-oyl-CoANot available
Average1132.02Da
Monoisotopic1131.321249356Da

Displaying 1–10 of 40 metabolites

Health Effects

No health effects information available for this bacterium.