Streptomyces clavuligerus

aerobic

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Kitasatosporales

Family

Streptomycetaceae

Genus

Streptomyces

Description

Streptomyces clavuligerus is a notable bacterium primarily found in soil environments. This species is an aerobic organism, requiring oxygen for its metabolic processes. It is categorized as mesophilic, thriving in moderate temperature ranges conducive to its growth and activity. One of the distinguishing features of S. clavuligerus is its true flagella, which enable motility and may play a role in its ecological interactions within the soil. Furthermore, the organism possesses a complex genomic structure characterized by 18 replicons, indicating a sophisticated genetic organization that may contribute to its adaptability and functionality in diverse soil conditions. S. clavuligerus is best known for its production of clavulanic acid, a β-lactamase inhibitor that has significant implications in antibiotic therapy, particularly in overcoming resistance in certain bacterial infections. This capability highlights the ecological role of S. clavuligerus within the soil microbiome, where it not only interacts with other microbial communities but also plays a part in the broader context of antibiotic resistance management. In summary, the presence of Streptomyces clavuligerus in soil environments, its aerobic nature, mesophilic temperature preference, motility through flagella, and notable genetic complexity underline its important ecological and biotechnological roles, particularly in the field of medicine.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderKitasatosporales
FamilyStreptomycetaceae
GenusStreptomyces
SpeciesStreptomyces clavuligerus
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Streptomyces clavuligerus
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsaerobic
Optimal temperatureNot Available
Temperature rangemesophilic
Habitatsoil
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Gene Summary

Adenine Count

925966 bp

Thymine Count

918184 bp

Guanine Count

2448180 bp

Cytosine Count

2456261 bp

Genome Length

6748591 bp

Protein-coding Genes

5536 genes

Non-Coding Genes

95 genes

# of Chromosomes/Plasmids

18

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
lipoyl(octanoyl) transferase lipbGE265_06795B1VZM4Positive1695991 - 169678529108.7
lipoyl synthaseGE265_06800Q9S2P2Positive1696997 - 169797436448.5
hypothetical proteinGE265_06805Not AvailablePositive1698332 - 16985959317.28
duf4191 family proteinGE265_06810P9WLI0Positive1698606 - 169931325085.4
rdd family proteinGE265_06815Not AvailableNegative1699433 - 169990316780.7
type i glutamate--ammonia ligaseGE265_06820P77958Positive1700127 - 170153652238.2
hypothetical proteinGE265_06825Not AvailableNegative1701719 - 17019287563.74
hypothetical proteinGE265_06830Not AvailablePositive1702263 - 170312631260.3
hypothetical proteinGE265_06835Not AvailablePositive1703176 - 17034459939.93
hypothetical proteinGE265_06840Not AvailableNegative1703499 - 170446135905.5

Displaying genes 8521 – 8530 of 29387 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

22 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0002002glyoxylateC2HO3Chemical structure of glyoxylateNot available
Average73.0275Da
Monoisotopic72.9925689Da
BASm0003389NADP(+)C21H25N7O17P3Chemical structure of NADP(+)Not available
Average740.386Da
Monoisotopic740.053624107Da
BASm0003563N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valineC14H24N3O6SChemical structure of N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valineNot available
Average362.42Da
Monoisotopic362.1391303Da
BASm0003686(2E,6E,10E)-geranylgeranyl diphosphateC20H33O7P2Chemical structure of (2E,6E,10E)-geranylgeranyl diphosphateNot available
Average447.426Da
Monoisotopic447.171798138Da
BASm0014202N-ButyrylglycineC6H11NO3Chemical structure of N-ButyrylglycineNULL
Average145.1564Da
Monoisotopic145.073893223Da
BASm0019999AllysineC6H11NO3Chemical structure of Allysine1962-83-0
Average145.1564Da
Monoisotopic145.0738932Da
BASm0034713EucalyptolC10H18OChemical structure of EucalyptolNULL
Average154.253Da
Monoisotopic154.1357652Da

Displaying 1–10 of 22 metabolites

Health Effects

No health effects information available for this bacterium.