Nocardia asteroides

Rodmicroaerophile

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Nocardiaceae

Genus

Nocardia

Description

Nocardia asteroides is a Gram-positive bacterium characterized by its rod shape and the presence of flagella. It is classified as a microaerophile, requiring lower levels of oxygen for growth compared to typical aerobic organisms. N. asteroides has two replicons, which are essential for its genetic replication and stability. This bacterium primarily affects Homo sapiens, leading to various health complications. Notably, it can cause pneumonia and more severe conditions such as disseminated nocardiosis, which refers to the spread of the infection throughout the body. Additionally, it is associated with actinomycetoma, a chronic infection that affects the skin and subcutaneous tissues. The health implications of N. asteroides highlight its significance as a pathogenic organism. Its ability to cause disseminated disease underscores the importance of understanding its ecological niche and interactions with human hosts. This bacterium's presence in the environment and its pathogenic potential can inform clinical practices and public health measures aimed at preventing infections, particularly in immunocompromised individuals. The accessions CP082844.1 and CP082845.1 provide genetic information that can further enhance our understanding of its biology and pathogenic mechanisms.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyNocardiaceae
GenusNocardia
SpeciesNocardia asteroides
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Nocardia asteroides
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsmicroaerophile
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Nocardia asteroides , Complete Genome

Gene Summary

Adenine Count

1172318 bp

Thymine Count

1181754 bp

Guanine Count

2503892 bp

Cytosine Count

2499799 bp

Genome Length

7357763 bp

Protein-coding Genes

6573 genes

Non-Coding Genes

73 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
abc transporter permease subunitK8O92_01890Not AvailableNegative408909 - 40979934166.7
tetr/acrr family transcriptional regulatorK8O92_01895P9WMD0Negative409796 - 41041022279.8
dihydroxy-acid dehydrataseK8O92_01900Q5Z0M2Negative410619 - 41232559223.3
helix-turn-helix domain-containing proteinK8O92_01905A0QVU1Positive412464 - 41285014131.9
atp-dependent clp protease proteolytic subunitK8O92_01910Q5Z0M4Negative412851 - 41344421527.8
atp-dependent clp protease proteolytic subunitK8O92_01915Q4JWV4Negative413742 - 41434721906.2
hypothetical proteinK8O92_01920Not AvailableNegative414702 - 41627056619.3
tetr/acrr family transcriptional regulatorK8O92_01925A0R666Negative416622 - 41722722549.8
acyl-coa dehydrogenase family proteinK8O92_01930Q5ZHT1Positive417318 - 41852644314.0
phosphotransferase family proteinK8O92_01935Q8K370Positive418523 - 41957838972.3

Displaying genes 391 – 400 of 6699 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4 records
Metabolite IDMetabolite nameStructureCAS number
BASm0014399Asterobactin AC34H55N7O13Chemical structure of Asterobactin ANULL
Average769.85Da
Monoisotopic769.385784859Da
BASm0014479Asterobactin CC37H61N7O13Chemical structure of Asterobactin CNULL
Average811.931Da
Monoisotopic811.432735052Da
BASm0015183Asterobactin BC35H57N7O13Chemical structure of Asterobactin BNULL
Average783.877Da
Monoisotopic783.401434923Da
BASm0039655Achromobacter xylosoxidans A8Not availableNot availableNot available

Displaying 1–4 of 4 metabolites

Health Effects

Health ConditionRelationReference
Disseminated nocardiosisCausesPMC9112502
Disseminated diseaseCausesPMC9112502
PneumoniaCausesPMC9112502
ActinomycetomaCausesPMC9780526
InfectionsCausesPMC12139244

Displaying health effects 1 – 5 of 5 in total