Nocardia asteroides 727, GA 875, M 170-6, M170-6

Rodmicroaerophile

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Nocardiaceae

Genus

Nocardia

Description

Nocardia asteroides is a Gram-positive, microaerophilic bacterium characterized by its rod shape and the presence of flagella. This organism is notable for its pathogenic potential in humans, particularly as it can lead to severe health complications including pneumonia, disseminated nocardiosis, disseminated disease, and actinomycetoma. The strain Nocardia asteroides 727 is one of the identified variants, along with GA 875 and M 170-6. These strains possess a single replicon, which is typical for this genus. The presence of flagella suggests that these bacteria may have motility advantages that could facilitate their spread within host tissues or environments. The primary host for N. asteroides is Homo sapiens, indicating its relevance in clinical microbiology. The pathogenic nature of this bacterium is particularly concerning in immunocompromised individuals, where infections can escalate quickly and may require aggressive treatment strategies. Ecologically, Nocardia species, including N. asteroides, are often found in soil and decaying organic matter. Their ability to thrive in microaerophilic conditions may provide insights into their environmental resilience and interactions with other microorganisms. Understanding the traits of N. asteroides can aid in developing effective diagnostic and therapeutic measures for infections it causes, particularly in vulnerable populations. The accession number for this strain is LR134352.1, which can be used for further research and reference in scientific databases.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyNocardiaceae
GenusNocardia
SpeciesNocardia asteroides
Strain727, GA 875, M 170-6, M170-6

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Nocardia asteroides 727, GA 875, M 170-6, M170-6
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsmicroaerophile
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Nocardia asteroides 727, GA 875, M 170-6, M170-6, Complete Genome

Gene Summary

Adenine Count

1052783 bp

Thymine Count

1050898 bp

Guanine Count

2444230 bp

Cytosine Count

2435452 bp

Genome Length

6983363 bp

Protein-coding Genes

6348 genes

Non-Coding Genes

82 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
probable ribonuclease fitbNCTC11293_06415P55511Positive6905145 - 690557615850.1
nitrogen regulation protein cNCTC11293_06416O32197Negative6905584 - 690620121334.8
sensor protein degsNCTC11293_06417O32198Negative6906198 - 690743943644.0
ftsx-like permease familyNCTC11293_06418Q4L8L8Positive6907569 - 690862135635.8
lipoprotein-releasing system atp-binding protein loldNCTC11293_06419Q3SRG8Positive6908633 - 690934324880.1
probable ribonuclease vapc47NCTC11293_06420P9WF50Negative6909354 - 690978815753.7
antitoxin vapb47NCTC11293_06421P9WF22Negative6909785 - 691006010191.2
uncharacterised proteinNCTC11293_06422Not AvailablePositive6910158 - 691055013807.4
hth-type transcriptional repressor kstr2NCTC11293_06423P95251Negative6910565 - 691117621822.2
methylmalonyl-coa carboxyltransferase 12s subunitNCTC11293_06424I6YDK7Positive6911271 - 691287857399.5

Displaying genes 6371 – 6380 of 6430 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Disseminated nocardiosisCausesPMC9112502
Disseminated diseaseCausesPMC9112502
PneumoniaCausesPMC9112502
ActinomycetomaCausesPMC9780526
InfectionsCausesPMC12139244

Displaying health effects 1 – 5 of 5 in total