Nocardia asteroides 727, GA 875, M 170-6, M170-6

Rodmicroaerophile

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Nocardiaceae

Genus

Nocardia

Description

Nocardia asteroides is a Gram-positive, microaerophilic bacterium characterized by its rod shape and the presence of flagella. This organism is notable for its pathogenic potential in humans, particularly as it can lead to severe health complications including pneumonia, disseminated nocardiosis, disseminated disease, and actinomycetoma. The strain Nocardia asteroides 727 is one of the identified variants, along with GA 875 and M 170-6. These strains possess a single replicon, which is typical for this genus. The presence of flagella suggests that these bacteria may have motility advantages that could facilitate their spread within host tissues or environments. The primary host for N. asteroides is Homo sapiens, indicating its relevance in clinical microbiology. The pathogenic nature of this bacterium is particularly concerning in immunocompromised individuals, where infections can escalate quickly and may require aggressive treatment strategies. Ecologically, Nocardia species, including N. asteroides, are often found in soil and decaying organic matter. Their ability to thrive in microaerophilic conditions may provide insights into their environmental resilience and interactions with other microorganisms. Understanding the traits of N. asteroides can aid in developing effective diagnostic and therapeutic measures for infections it causes, particularly in vulnerable populations. The accession number for this strain is LR134352.1, which can be used for further research and reference in scientific databases.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyNocardiaceae
GenusNocardia
SpeciesNocardia asteroides
Strain727, GA 875, M 170-6, M170-6

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Nocardia asteroides 727, GA 875, M 170-6, M170-6
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsmicroaerophile
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Nocardia asteroides 727, GA 875, M 170-6, M170-6, Complete Genome

Gene Summary

Adenine Count

1052783 bp

Thymine Count

1050898 bp

Guanine Count

2444230 bp

Cytosine Count

2435452 bp

Genome Length

6983363 bp

Protein-coding Genes

6348 genes

Non-Coding Genes

82 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hth-type transcriptional repressor yvoaNCTC11293_06204Q82IW0Positive6645392 - 664612327335.7
uncharacterised proteinNCTC11293_06205Not AvailablePositive6646187 - 66464628453.91
cholesterol oxidase precursorNCTC11293_06206P12676Negative6646504 - 664809955965.1
uncharacterized protein conserved in bacteriaNCTC11293_06207Not AvailableNegative6648146 - 664877521906.8
uncharacterised proteinNCTC11293_06208Not AvailableNegative6648772 - 665030453290.2
hth-type transcriptional repressor kstrNCTC11293_06209Q0S868Positive6650443 - 665104821694.0
uncharacterised proteinNCTC11293_06210Not AvailablePositive6651173 - 66513285269.94
uncharacterised proteinNCTC11293_06211Not AvailablePositive6651361 - 66515767556.31
polyketide cyclase / dehydrase and lipid transportNCTC11293_06212Not AvailableNegative6651642 - 665210916808.0
di-/tripeptide transporterNCTC11293_06213P94408Positive6652272 - 665375952431.6

Displaying genes 6161 – 6170 of 6430 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Disseminated nocardiosisCausesPMC9112502
Disseminated diseaseCausesPMC9112502
PneumoniaCausesPMC9112502
ActinomycetomaCausesPMC9780526
InfectionsCausesPMC12139244

Displaying health effects 1 – 5 of 5 in total