Nocardia asteroides 727, GA 875, M 170-6, M170-6

Rodmicroaerophile

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Nocardiaceae

Genus

Nocardia

Description

Nocardia asteroides is a Gram-positive, microaerophilic bacterium characterized by its rod shape and the presence of flagella. This organism is notable for its pathogenic potential in humans, particularly as it can lead to severe health complications including pneumonia, disseminated nocardiosis, disseminated disease, and actinomycetoma. The strain Nocardia asteroides 727 is one of the identified variants, along with GA 875 and M 170-6. These strains possess a single replicon, which is typical for this genus. The presence of flagella suggests that these bacteria may have motility advantages that could facilitate their spread within host tissues or environments. The primary host for N. asteroides is Homo sapiens, indicating its relevance in clinical microbiology. The pathogenic nature of this bacterium is particularly concerning in immunocompromised individuals, where infections can escalate quickly and may require aggressive treatment strategies. Ecologically, Nocardia species, including N. asteroides, are often found in soil and decaying organic matter. Their ability to thrive in microaerophilic conditions may provide insights into their environmental resilience and interactions with other microorganisms. Understanding the traits of N. asteroides can aid in developing effective diagnostic and therapeutic measures for infections it causes, particularly in vulnerable populations. The accession number for this strain is LR134352.1, which can be used for further research and reference in scientific databases.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyNocardiaceae
GenusNocardia
SpeciesNocardia asteroides
Strain727, GA 875, M 170-6, M170-6

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Nocardia asteroides 727, GA 875, M 170-6, M170-6
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsmicroaerophile
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Nocardia asteroides 727, GA 875, M 170-6, M170-6, Complete Genome

Gene Summary

Adenine Count

1052783 bp

Thymine Count

1050898 bp

Guanine Count

2444230 bp

Cytosine Count

2435452 bp

Genome Length

6983363 bp

Protein-coding Genes

6348 genes

Non-Coding Genes

82 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
l-lactate dehydrogenase (fmn-dependent) and related alpha-hydroxy acid dehydrogenasesNCTC11293_03743B2TEK6Positive3943660 - 394465834349.7
uncharacterised proteinNCTC11293_03744Not AvailablePositive3944776 - 39450219003.29
uncharacterised proteinNCTC11293_03745Not AvailablePositive3945109 - 394590030137.3
uncharacterised proteinNCTC11293_03746Not AvailableNegative3945901 - 394630816032.9
mycolyl transferase 85aNCTC11293_03747P0C1D6Positive3947023 - 394805136386.6
predicted ntpase (nacht family)NCTC11293_03748Not AvailableNegative3948207 - 395013568700.0
uncharacterised proteinNCTC11293_03749Not AvailableNegative3950283 - 39504807048.42
hypoxia sensor histidine kinase response regulator dostNCTC11293_03750P9WGK0Negative3951168 - 395291363137.1
transcriptional regulatory protein devr (dosr)NCTC11293_03751P9WMF8Negative3952961 - 395359322703.7
universal stress protein msmeg_3950NCTC11293_03752A0QZA1Negative3953647 - 395398811958.2

Displaying genes 3721 – 3730 of 6430 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Disseminated nocardiosisCausesPMC9112502
Disseminated diseaseCausesPMC9112502
PneumoniaCausesPMC9112502
ActinomycetomaCausesPMC9780526
InfectionsCausesPMC12139244

Displaying health effects 1 – 5 of 5 in total