Cutibacterium acnes subsp. acnes

RodNon-motileanaerobic

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Propionibacteriales

Family

Propionibacteriaceae

Genus

Cutibacterium

Description

Cutibacterium acnes subsp. acnes is a Gram-positive, anaerobic bacterium characterized by its rod shape and lack of mobility, as it does not possess flagella. This subspecies thrives optimally at a temperature of 37°C, categorizing it as mesophilic, which indicates its preference for moderate temperatures typical of human skin. C. acnes subsp. acnes is classified as free-living, highlighting its ability to exist independently in various environments, particularly on human skin where it is part of the normal microbiota. It is noteworthy that this bacterium has four replicons, which may contribute to its genetic diversity and adaptability in different conditions. The presence of C. acnes subsp. acnes on the skin is significant, as it plays a dual role in human health. While it is generally considered a commensal organism, its overgrowth can be associated with skin conditions such as acne. This duality reflects its potential impact on human health, suggesting that maintaining a balanced skin microbiome is essential for preventing the pathological effects associated with its proliferation. The accessions for this bacterium include CP023676.1, CP044255.1, CP025934.1, and AP019723.1, which provide genomic data that can further enhance understanding of its biology and ecological interactions within the human microbiome. Overall, C. acnes subsp. acnes exemplifies the complexity of microbial life and its significant role in human health and disease.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderPropionibacteriales
FamilyPropionibacteriaceae
GenusCutibacterium
SpeciesCutibacterium acnes
Strainsubsp. acnes

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Cutibacterium acnes subsp. acnes
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsanaerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatNot Available
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Cutibacterium acnes subsp. acnes , Complete Genome

Gene Summary

Adenine Count

497686 bp

Thymine Count

499617 bp

Guanine Count

747684 bp

Cytosine Count

750014 bp

Genome Length

2495001 bp

Protein-coding Genes

2450 genes

Non-Coding Genes

58 genes

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
sn-glycerol-3-phosphate dehydrogenase subunit cCacPP4_21440P0A997Negative2365456 - 236670645682.2
anaerobic glycerol-3-phosphate dehydrogenase subunit bCacPP4_21450Q6CZI7Negative2366709 - 236805246489.8
glycerol-3-phosphate dehydrogenaseCacPP4_21460D4GYI2Negative2368049 - 236967459088.6
d-glycerate dehydrogenaseCacPP4_21470Q9C4M5Negative2370100 - 237106534110.0
hypothetical proteinCacPP4_21480P0A2T5Positive2370979 - 237164723980.0
hypothetical proteinCacPP4_21490Q8XTT4Positive2371644 - 237337159585.5
amino acid transporterCacPP4_21500P46349Negative2373374 - 237478048999.2
marr family transcriptional regulatorCacPP4_21510A7FHL4Negative2374896 - 237538718270.8
dna repair exonucleaseCacPP4_21520O07522Positive2375760 - 237690541407.3
hypothetical proteinCacPP4_21530P9WM40Positive2376902 - 237950896265.1

Displaying genes 9731 – 9740 of 9832 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

No health effects information available for this bacterium.