Cutibacterium acnes subsp. acnes

RodNon-motileanaerobic

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Propionibacteriales

Family

Propionibacteriaceae

Genus

Cutibacterium

Description

Cutibacterium acnes subsp. acnes is a Gram-positive, anaerobic bacterium characterized by its rod shape and lack of mobility, as it does not possess flagella. This subspecies thrives optimally at a temperature of 37°C, categorizing it as mesophilic, which indicates its preference for moderate temperatures typical of human skin. C. acnes subsp. acnes is classified as free-living, highlighting its ability to exist independently in various environments, particularly on human skin where it is part of the normal microbiota. It is noteworthy that this bacterium has four replicons, which may contribute to its genetic diversity and adaptability in different conditions. The presence of C. acnes subsp. acnes on the skin is significant, as it plays a dual role in human health. While it is generally considered a commensal organism, its overgrowth can be associated with skin conditions such as acne. This duality reflects its potential impact on human health, suggesting that maintaining a balanced skin microbiome is essential for preventing the pathological effects associated with its proliferation. The accessions for this bacterium include CP023676.1, CP044255.1, CP025934.1, and AP019723.1, which provide genomic data that can further enhance understanding of its biology and ecological interactions within the human microbiome. Overall, C. acnes subsp. acnes exemplifies the complexity of microbial life and its significant role in human health and disease.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderPropionibacteriales
FamilyPropionibacteriaceae
GenusCutibacterium
SpeciesCutibacterium acnes
Strainsubsp. acnes

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Cutibacterium acnes subsp. acnes
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsanaerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatNot Available
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Cutibacterium acnes subsp. acnes , Complete Genome

Gene Summary

Adenine Count

497686 bp

Thymine Count

499617 bp

Guanine Count

747684 bp

Cytosine Count

750014 bp

Genome Length

2495001 bp

Protein-coding Genes

2450 genes

Non-Coding Genes

58 genes

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
adenylosuccinate lyaseF6X01_10615Q05911Negative2116505 - 211793852233.6
phosphoribosylamine--glycine ligaseF6X01_10620Q9RKL4Negative2117935 - 211925445326.4
adenylosuccinate synthaseF6X01_10625Q6A6A3Negative2119313 - 212061147475.5
gnat family n-acetyltransferaseF6X01_10630Not AvailableNegative2120767 - 212167832596.4
fadr family transcriptional regulatorF6X01_10635P42239Positive2121796 - 212253026850.1
n-acetylmannosamine-6-phosphate 2-epimeraseF6X01_10640Q6A6A0Negative2122655 - 212334424027.7
dihydrodipicolinate synthase family proteinF6X01_10645B9K865Negative2123377 - 212434834567.6
duf4862 family proteinF6X01_10650A1XPK1Negative2124345 - 212524732115.0
mfs transporterF6X01_10655B1JFW5Negative2125272 - 212687657794.6
duf3151 domain-containing proteinF6X01_10660Not AvailableNegative2127004 - 212753119155.8

Displaying genes 4631 – 4640 of 9832 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

No health effects information available for this bacterium.