Cutibacterium acnes subsp. acnes

RodNon-motileanaerobic

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Propionibacteriales

Family

Propionibacteriaceae

Genus

Cutibacterium

Description

Cutibacterium acnes subsp. acnes is a Gram-positive, anaerobic bacterium characterized by its rod shape and lack of mobility, as it does not possess flagella. This subspecies thrives optimally at a temperature of 37°C, categorizing it as mesophilic, which indicates its preference for moderate temperatures typical of human skin. C. acnes subsp. acnes is classified as free-living, highlighting its ability to exist independently in various environments, particularly on human skin where it is part of the normal microbiota. It is noteworthy that this bacterium has four replicons, which may contribute to its genetic diversity and adaptability in different conditions. The presence of C. acnes subsp. acnes on the skin is significant, as it plays a dual role in human health. While it is generally considered a commensal organism, its overgrowth can be associated with skin conditions such as acne. This duality reflects its potential impact on human health, suggesting that maintaining a balanced skin microbiome is essential for preventing the pathological effects associated with its proliferation. The accessions for this bacterium include CP023676.1, CP044255.1, CP025934.1, and AP019723.1, which provide genomic data that can further enhance understanding of its biology and ecological interactions within the human microbiome. Overall, C. acnes subsp. acnes exemplifies the complexity of microbial life and its significant role in human health and disease.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderPropionibacteriales
FamilyPropionibacteriaceae
GenusCutibacterium
SpeciesCutibacterium acnes
Strainsubsp. acnes

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Cutibacterium acnes subsp. acnes
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsanaerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatNot Available
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Cutibacterium acnes subsp. acnes , Complete Genome

Gene Summary

Adenine Count

497686 bp

Thymine Count

499617 bp

Guanine Count

747684 bp

Cytosine Count

750014 bp

Genome Length

2495001 bp

Protein-coding Genes

2450 genes

Non-Coding Genes

58 genes

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
tryptophan synthase subunit betaF6X01_06065Q6AF67Positive1202876 - 120413245245.8
tryptophan synthase subunit alphaF6X01_06070A0QHG8Positive1204129 - 120462617365.6
prolipoprotein diacylglyceryl transferaseF6X01_06075Q6A8N5Positive1204623 - 120546231439.3
glutamate synthase large subunitF6X01_06080P96218Positive1205584 - 1210101164422.0
glutamate synthase subunit betaF6X01_06085P9WN18Positive1210094 - 121156653343.4
hypothetical proteinF6X01_06090Not AvailablePositive1211603 - 121193211797.9
penicillin binding protein pbp4bF6X01_06095Q8XBJ0Positive1211942 - 121413180976.8
hypothetical proteinF6X01_06100Not AvailableNegative1214230 - 121487723039.3
murr/rpir family transcriptional regulatorF6X01_06105Q8RD36Negative1214887 - 121576831469.9
n-acetylmuramic acid 6-phosphate etheraseF6X01_06110Q6A8M7Positive1215885 - 121679931299.7

Displaying genes 3721 – 3730 of 9832 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

No health effects information available for this bacterium.