Cutibacterium acnes subsp. acnes

RodNon-motileanaerobic

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Propionibacteriales

Family

Propionibacteriaceae

Genus

Cutibacterium

Description

Cutibacterium acnes subsp. acnes is a Gram-positive, anaerobic bacterium characterized by its rod shape and lack of mobility, as it does not possess flagella. This subspecies thrives optimally at a temperature of 37°C, categorizing it as mesophilic, which indicates its preference for moderate temperatures typical of human skin. C. acnes subsp. acnes is classified as free-living, highlighting its ability to exist independently in various environments, particularly on human skin where it is part of the normal microbiota. It is noteworthy that this bacterium has four replicons, which may contribute to its genetic diversity and adaptability in different conditions. The presence of C. acnes subsp. acnes on the skin is significant, as it plays a dual role in human health. While it is generally considered a commensal organism, its overgrowth can be associated with skin conditions such as acne. This duality reflects its potential impact on human health, suggesting that maintaining a balanced skin microbiome is essential for preventing the pathological effects associated with its proliferation. The accessions for this bacterium include CP023676.1, CP044255.1, CP025934.1, and AP019723.1, which provide genomic data that can further enhance understanding of its biology and ecological interactions within the human microbiome. Overall, C. acnes subsp. acnes exemplifies the complexity of microbial life and its significant role in human health and disease.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderPropionibacteriales
FamilyPropionibacteriaceae
GenusCutibacterium
SpeciesCutibacterium acnes
Strainsubsp. acnes

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Cutibacterium acnes subsp. acnes
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsanaerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatNot Available
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Cutibacterium acnes subsp. acnes , Complete Genome

Gene Summary

Adenine Count

497686 bp

Thymine Count

499617 bp

Guanine Count

747684 bp

Cytosine Count

750014 bp

Genome Length

2495001 bp

Protein-coding Genes

2450 genes

Non-Coding Genes

58 genes

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nadh-quinone oxidoreductase subunit kCPA42_10205Q6A6G8Negative2035057 - 203535610655.3
nadh:ubiquinone oxidoreductase subunit jCPA42_10210P50975Negative2035353 - 203620729668.7
nadh-quinone oxidoreductase subunit nuoiCPA42_10215Q6A6G6Negative2036207 - 203680622469.2
nadh-quinone oxidoreductase subunit hCPA42_10220Q6A6G5Negative2036803 - 203812548321.4
nadh-quinone oxidoreductase subunit gCPA42_10225P59962Negative2038122 - 204056086613.4
nadh-quinone oxidoreductase subunit fCPA42_10230Q9XAQ9Negative2040557 - 204189148520.0
nadh-quinone oxidoreductase subunit nuoeCPA42_10235P65574Negative2041888 - 204267328439.4
nadh-quinone oxidoreductase subunit nuodCPA42_10240Q6A6G1Negative2042670 - 204397148012.4
nadh-quinone oxidoreductase subunit cCPA42_10245A1SE29Negative2043971 - 204479530589.9
nadh-quinone oxidoreductase subunit bCPA42_10250Q6A6F9Negative2044792 - 204535820817.5

Displaying genes 2041 – 2050 of 9832 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

No health effects information available for this bacterium.