Kytococcus sedentarius DM 51

Gram-positiveCocciNon-motileAerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Micrococcales

Family

Kytococcaceae

Genus

Kytococcus

Description

Kytococcus sedentarius DM 51 is a Gram-positive, aerobic cocci bacterium that predominantly inhabits human skin. It is characterized by its unique tetrad cell arrangement and the absence of mobility, as it lacks flagella. This bacterium thrives optimally at 29°C and falls within the mesophilic temperature range, which indicates its preference for moderate temperatures typical of human body environments. Kytococcus sedentarius is free-living, meaning it does not depend on a host for survival beyond its association with Homo sapiens. It is known to be associated with a specific health condition known as pitted keratolysis, a skin disorder that affects the feet and can lead to superficial skin lesions. The presence of this bacterium in the skin microbiome may play a role in skin health and disease, particularly in the context of moisture-rich environments where pitted keratolysis is more likely to occur. The genome of Kytococcus sedentarius DM 51 is represented by accession number CP069495.1, indicating the availability of genetic information for further research. Understanding the ecological role of Kytococcus sedentarius on human skin can provide insights into microbial interactions and the potential implications for skin health, especially concerning its pathogenic potential in specific conditions like pitted keratolysis.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMicrococcales
FamilyKytococcaceae
GenusKytococcus
SpeciesKytococcus sedentarius
StrainDM 51

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Kytococcus sedentarius DM 51
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature29
Temperature rangeMesophilic
Habitatskin
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementTetrads
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Kytococcus sedentarius DM 51, Complete Genome

Gene Summary

Adenine Count

343437 bp

Thymine Count

342145 bp

Guanine Count

880784 bp

Cytosine Count

882390 bp

Genome Length

2448756 bp

Protein-coding Genes

2253 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
aminomethyl-transferring glycine dehydrogenaseI6J30_05860Q827D7Negative1231573 - 1234455102454.0
merr family transcriptional regulatorI6J30_05865P9WME4Negative1234752 - 123530319378.9
merr family transcriptional regulatorI6J30_05870P9WME6Negative1235437 - 123614725721.8
fha domain-containing proteinI6J30_05875A0QYG2Negative1236144 - 123659915832.4
glycine cleavage system protein gcvhI6J30_05880Q2NRE9Negative1236674 - 123706314007.0
duf881 domain-containing proteinI6J30_05885P9WFG2Negative1237127 - 123787326756.5
small basic family proteinI6J30_05890P9WLR6Negative1237866 - 123819811659.7
duf881 domain-containing proteinI6J30_05895P9WFG0Negative1238195 - 123902529767.3
formate dehydrogenase accessory sulfurtransferase fdhdI6J30_05900P64119Negative1239092 - 123993729425.1
fad-dependent oxidoreductaseI6J30_05905Q5L2C2Positive1240149 - 124127939645.7

Displaying genes 1171 – 1180 of 2309 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Pitted keratolysisCausesPMC11939757
Valve endocarditisCausesPMC3035214
Hemorrhagic pneumoniaCausesPMC3035214
Pitted keratolysisCausesPMC3035214
Infectious spondylitisCausesPMC8400003

Displaying health effects 1 – 5 of 5 in total