Enterococcus faecium strain H323

Gram-positiveCocciFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Enterococcaceae

Genus

Enterococcus

Description

Enterococcus faecium strain H323 is a Gram-positive bacterium primarily found in fermented mare milk. This strain exhibits a cocci shape and is classified as a facultative anaerobe, indicating its ability to thrive in both aerobic and anaerobic environments. Notably, it possesses flagella, which contribute to its motility. E. faecium strain H323 has been associated with various hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and several other species across the Metazoa kingdom. This broad host range suggests its ecological versatility and potential interactions within diverse environments. Health effects linked to this strain are significant, particularly in human populations, where it has been implicated in various serious conditions. These include endocarditis, bloodstream infections, urinary tract infections, biliary tract infections, and nosocomial infections. Its pathogenicity in humans highlights its potential as a clinical concern, especially in hospital settings, where it can lead to nosocomial bacteremia and systemic infections. The presence of E. faecium strain H323 in fermented mare milk and its association with human infections raise important ecological and health considerations. The strain's ability to inhabit both food sources and cause disease underscores the complex relationship between beneficial and pathogenic microorganisms in human health and food safety. Understanding such dynamics is crucial for developing effective strategies for managing infections caused by E. faecium and ensuring the safety of fermented dairy products.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyEnterococcaceae
GenusEnterococcus
SpeciesEnterococcus faecium
Strainstrain H323

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Enterococcus faecium strain H323
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatfermented mare milk
Biotic relationshipNot Available
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Enterococcus faecium strain H323

Gene Summary

Adenine Count

910360 bp

Thymine Count

904155 bp

Guanine Count

554701 bp

Cytosine Count

543855 bp

Genome Length

2913071 bp

Protein-coding Genes

2875 genes

Non-Coding Genes

107 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
abc transporter substrate-binding proteinFIU43_00895Not AvailableNegative182388 - 18340438335.1
sugar abc transporter substrate-binding proteinFIU43_00900Not AvailablePositive183624 - 18471239048.9
sugar abc transporter atp-binding proteinFIU43_00905Not AvailablePositive184766 - 18629256729.8
sugar abc transporter permeaseFIU43_00910Not AvailablePositive186294 - 18749942863.1
gmp reductaseFIU43_00915Not AvailablePositive187756 - 18873335972.5
plp-dependent aminotransferase family proteinFIU43_00925Not AvailablePositive188997 - 19042154745.4
hypothetical proteinFIU43_00930Not AvailableNegative190463 - 19072010091.7
pyruvate dehydrogenase (acetyl-transferring) e1 component subunit alphaFIU43_00935Not AvailablePositive190882 - 19199140899.3
alpha-ketoacid dehydrogenase subunit betaFIU43_00940Not AvailablePositive191994 - 19297135518.4
dihydrolipoyllysine-residue acetyltransferaseFIU43_00945Not AvailablePositive192996 - 19463957977.2

Displaying genes 231 – 240 of 2982 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Urinary tract infectionsCausesPMC11784074
EndocarditisCausesPMC11784074
Bloodstream infectionsCausesPMC11784074
Human infectionCausesPMC6222123
Nosocomial infectionCausesPMC6222123
EndocarditisCausesPMC6385395
Infected pancreatic necrosisCausesPMC9466706
Systemic infectionCausesPMC9466706
Nosocomial infectionsCausesPMC5727370
Urinary tract infectionsCausesPMC8879582

Displaying health effects 1 – 10 of 13 in total