Enterococcus faecium strain H323

Gram-positiveCocciFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Enterococcaceae

Genus

Enterococcus

Description

Enterococcus faecium strain H323 is a Gram-positive bacterium primarily found in fermented mare milk. This strain exhibits a cocci shape and is classified as a facultative anaerobe, indicating its ability to thrive in both aerobic and anaerobic environments. Notably, it possesses flagella, which contribute to its motility. E. faecium strain H323 has been associated with various hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and several other species across the Metazoa kingdom. This broad host range suggests its ecological versatility and potential interactions within diverse environments. Health effects linked to this strain are significant, particularly in human populations, where it has been implicated in various serious conditions. These include endocarditis, bloodstream infections, urinary tract infections, biliary tract infections, and nosocomial infections. Its pathogenicity in humans highlights its potential as a clinical concern, especially in hospital settings, where it can lead to nosocomial bacteremia and systemic infections. The presence of E. faecium strain H323 in fermented mare milk and its association with human infections raise important ecological and health considerations. The strain's ability to inhabit both food sources and cause disease underscores the complex relationship between beneficial and pathogenic microorganisms in human health and food safety. Understanding such dynamics is crucial for developing effective strategies for managing infections caused by E. faecium and ensuring the safety of fermented dairy products.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyEnterococcaceae
GenusEnterococcus
SpeciesEnterococcus faecium
Strainstrain H323

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Enterococcus faecium strain H323
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatfermented mare milk
Biotic relationshipNot Available
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Enterococcus faecium strain H323

Gene Summary

Adenine Count

910360 bp

Thymine Count

904155 bp

Guanine Count

554701 bp

Cytosine Count

543855 bp

Genome Length

2913071 bp

Protein-coding Genes

2875 genes

Non-Coding Genes

107 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
multidrug efflux mfs transporterFIU43_09065Not AvailablePositive1799233 - 180052546753.9
aminotransferaseFIU43_09070Not AvailableNegative1800585 - 180170341625.9
arginine-ornithine antiporterFIU43_09075Not AvailableNegative1801717 - 180313850875.8
trna 2-thiouridine(34) synthase mnmaFIU43_09080Not AvailableNegative1803384 - 180450541567.3
metallophosphataseFIU43_09085Not AvailablePositive1804909 - 180550823389.7
duf1146 domain-containing proteinFIU43_09090Not AvailablePositive1805962 - 18061928907.19
udp-n-acetylglucosamine 1-carboxyvinyltransferaseFIU43_09095Not AvailablePositive1806289 - 180759047069.0
dna-directed rna polymerase subunit betaFIU43_09100Not AvailablePositive1807603 - 18077796601.54
membrane protein insertion efficiency factor yiddFIU43_09105Not AvailablePositive1807914 - 180821011305.0
gnat family n-acetyltransferaseFIU43_09110Not AvailablePositive1808394 - 180886117626.2

Displaying genes 1781 – 1790 of 2982 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Urinary tract infectionsCausesPMC11784074
EndocarditisCausesPMC11784074
Bloodstream infectionsCausesPMC11784074
Human infectionCausesPMC6222123
Nosocomial infectionCausesPMC6222123
EndocarditisCausesPMC6385395
Infected pancreatic necrosisCausesPMC9466706
Systemic infectionCausesPMC9466706
Nosocomial infectionsCausesPMC5727370
Urinary tract infectionsCausesPMC8879582

Displaying health effects 1 – 10 of 13 in total