Enterococcus faecium strain 4275

Gram-positiveCocciFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Enterococcaceae

Genus

Enterococcus

Description

Enterococcus faecium strain 4275 is a Gram-positive, facultative anaerobic bacterium characterized by its cocci shape. This strain is notably associated with fermented mare milk, suggesting a niche within dairy fermentation processes. It possesses flagella, which may contribute to its motility and adaptability in various environments. E. faecium strain 4275 has been identified in multiple hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and various other animals, indicating a broad ecological presence. This versatility in hosts may facilitate its transmission and persistence in different environments, including agricultural settings. Health-wise, Enterococcus faecium is recognized for its pathogenic potential in humans, being linked to several serious conditions such as endocarditis, bloodstream infections, and urinary tract infections. The strain is also implicated in nosocomial infections, which are infections acquired in healthcare settings, suggesting a significant public health concern due to its ability to cause systemic infections and bacteremia. The presence of E. faecium strain 4275 in fermented products and its ability to cause infections highlight its dual role in human health and food microbiology. Its significance in fermented mare milk may also indicate potential health benefits or risks associated with dairy consumption, emphasizing the need for further research on its pathogenicity and ecological role in both natural and clinical environments. The accessions for this strain, specifically VFBX00000000.1, provide a reference for further genomic studies that could elucidate its characteristics and behavior in different contexts.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyEnterococcaceae
GenusEnterococcus
SpeciesEnterococcus faecium
Strainstrain 4275

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Enterococcus faecium strain 4275
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatfermented mare milk
Biotic relationshipNot Available
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Enterococcus faecium strain 4275

Gene Summary

Adenine Count

911592 bp

Thymine Count

923318 bp

Guanine Count

552881 bp

Cytosine Count

560737 bp

Genome Length

2948528 bp

Protein-coding Genes

2852 genes

Non-Coding Genes

112 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hamp domain-containing histidine kinaseFIU64_13240Not AvailableNegative2572586 - 257392651212.4
response regulator transcription factorFIU64_13245Not AvailableNegative2573931 - 257460525880.7
ftsx-like permease family proteinFIU64_13250Not AvailablePositive2574827 - 257590039089.3
abc transporter atp-binding proteinFIU64_13255Not AvailablePositive2575906 - 257659225553.8
tetr/acrr family transcriptional regulatorFIU64_13260Not AvailablePositive2576600 - 257724725831.0
duf1694 domain-containing proteinFIU64_13270Not AvailableNegative2578579 - 257903117270.6
iron chelate uptake abc transporter family permease subunitFIU64_13275Not AvailablePositive2579181 - 258013134451.8
iron chelate uptake abc transporter family permease subunitFIU64_13280Not AvailablePositive2580124 - 258108335790.0
atp-binding cassette domain-containing proteinFIU64_13285Not AvailablePositive2581080 - 258183528528.8
siderophore abc transporter substrate-binding proteinFIU64_13290Not AvailablePositive2581858 - 258281134307.2

Displaying genes 2541 – 2550 of 2964 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Urinary tract infectionsCausesPMC11784074
EndocarditisCausesPMC11784074
Bloodstream infectionsCausesPMC11784074
Human infectionCausesPMC6222123
Nosocomial infectionCausesPMC6222123
EndocarditisCausesPMC6385395
Infected pancreatic necrosisCausesPMC9466706
Systemic infectionCausesPMC9466706
Nosocomial infectionsCausesPMC5727370
Urinary tract infectionsCausesPMC8879582

Displaying health effects 1 – 10 of 13 in total