Enterococcus faecium strain 4275

Gram-positiveCocciFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Enterococcaceae

Genus

Enterococcus

Description

Enterococcus faecium strain 4275 is a Gram-positive, facultative anaerobic bacterium characterized by its cocci shape. This strain is notably associated with fermented mare milk, suggesting a niche within dairy fermentation processes. It possesses flagella, which may contribute to its motility and adaptability in various environments. E. faecium strain 4275 has been identified in multiple hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and various other animals, indicating a broad ecological presence. This versatility in hosts may facilitate its transmission and persistence in different environments, including agricultural settings. Health-wise, Enterococcus faecium is recognized for its pathogenic potential in humans, being linked to several serious conditions such as endocarditis, bloodstream infections, and urinary tract infections. The strain is also implicated in nosocomial infections, which are infections acquired in healthcare settings, suggesting a significant public health concern due to its ability to cause systemic infections and bacteremia. The presence of E. faecium strain 4275 in fermented products and its ability to cause infections highlight its dual role in human health and food microbiology. Its significance in fermented mare milk may also indicate potential health benefits or risks associated with dairy consumption, emphasizing the need for further research on its pathogenicity and ecological role in both natural and clinical environments. The accessions for this strain, specifically VFBX00000000.1, provide a reference for further genomic studies that could elucidate its characteristics and behavior in different contexts.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyEnterococcaceae
GenusEnterococcus
SpeciesEnterococcus faecium
Strainstrain 4275

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Enterococcus faecium strain 4275
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatfermented mare milk
Biotic relationshipNot Available
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Enterococcus faecium strain 4275

Gene Summary

Adenine Count

911592 bp

Thymine Count

923318 bp

Guanine Count

552881 bp

Cytosine Count

560737 bp

Genome Length

2948528 bp

Protein-coding Genes

2852 genes

Non-Coding Genes

112 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
triphosphoribosyl-dephospho-coa synthase mdcbFIU64_08565Not AvailableNegative1693969 - 169483832180.1
acyltransferaseFIU64_08570Not AvailableNegative1694863 - 169593941520.4
malonate decarboxylase holo-acp synthaseFIU64_08575Not AvailableNegative1695963 - 169655622632.2
biotin-independent malonate decarboxylase subunit betaFIU64_08580Not AvailableNegative1696560 - 169823660438.0
malonate decarboxylase subunit deltaFIU64_08585Not AvailableNegative1698226 - 169852511104.3
malonate decarboxylase subunit alphaFIU64_08590Not AvailableNegative1698627 - 170027360214.2
acp s-malonyltransferaseFIU64_08595Not AvailableNegative1700280 - 170119133999.0
lysr family transcriptional regulatorFIU64_08600Not AvailablePositive1701311 - 170216832601.9
hypothetical proteinFIU64_08605Not AvailableNegative1702355 - 170271714191.1
hypothetical proteinFIU64_08610Not AvailableNegative1702906 - 17030886955.28

Displaying genes 1701 – 1710 of 2964 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Urinary tract infectionsCausesPMC11784074
EndocarditisCausesPMC11784074
Bloodstream infectionsCausesPMC11784074
Human infectionCausesPMC6222123
Nosocomial infectionCausesPMC6222123
EndocarditisCausesPMC6385395
Infected pancreatic necrosisCausesPMC9466706
Systemic infectionCausesPMC9466706
Nosocomial infectionsCausesPMC5727370
Urinary tract infectionsCausesPMC8879582

Displaying health effects 1 – 10 of 13 in total