Escherichia coli strain A240

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain A240 is a Gram-negative, rod-shaped bacterium that displays a facultative anaerobic metabolism. This strain is capable of moving due to the presence of flagella and typically arranges itself in pairs or as singles. A240 thrives optimally at a temperature of 37°C, categorizing it as mesophilic. It is characterized by having a single replicon and two membranes. This strain has a diverse range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and various other species across multiple taxa such as mammals, reptiles, and even plants like Solanum lycopersicum (tomatoes) and Brassica oleracea var. italica (broccoli). The ability of E. coli A240 to inhabit a variety of host organisms highlights its adaptability and potential for establishing complex biotic relationships. E. coli A240 is associated with a wide spectrum of health effects, particularly in humans, where it can cause conditions such as urinary tract infections (UTIs), gastrointestinal infections, and even severe complications like hemolytic uremic syndrome (HUS). Its pathogenicity is primarily linked to human hosts, indicating its significance in clinical microbiology and public health. The ecological insight derived from E. coli A240's wide host range and pathogenic potential suggests its role in both environmental and health-related contexts. Its presence in various hosts underscores the importance of monitoring this strain to mitigate its impact on health and understand its ecological dynamics within different environments.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain A240

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain A240
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain A240

Gene Summary

Adenine Count

1252467 bp

Thymine Count

1251742 bp

Guanine Count

1263020 bp

Cytosine Count

1280235 bp

Genome Length

5047464 bp

Protein-coding Genes

4657 genes

Non-Coding Genes

228 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
cytochrome c nitrite reductase fe-s proteinFIM11_15180Not AvailablePositive3146865 - 314753624568.8
cytochrome c nitrite reductase subunit nrfdFIM11_15185Not AvailablePositive3147533 - 314848935074.4
heme lyase ccmf/nrfe family subunitFIM11_15190Not AvailablePositive3148509 - 315022763641.2
heme lyase nrfefg subunit nrffFIM11_15195Not AvailablePositive3150220 - 315060314543.0
heme lyase nrfefg subunit nrfgFIM11_15200Not AvailablePositive3150600 - 315119622773.6
glutamate/aspartate:proton symporter gltpFIM11_15205Not AvailablePositive3151538 - 315285147107.0
sel1 repeat family proteinFIM11_15210Not AvailableNegative3152929 - 315361825080.4
formate dehydrogenase subunit alphaFIM11_15215Not AvailableNegative3153712 - 315585979228.1
multidrug efflux transporter outer membrane subunit mdtpFIM11_15220Not AvailableNegative3156057 - 315752353495.4
multidrug efflux transporter permease subunit mdtoFIM11_15225Not AvailableNegative3157520 - 315957176228.3

Displaying genes 3081 – 3090 of 4885 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total