Escherichia coli strain A240

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain A240 is a Gram-negative, rod-shaped bacterium that displays a facultative anaerobic metabolism. This strain is capable of moving due to the presence of flagella and typically arranges itself in pairs or as singles. A240 thrives optimally at a temperature of 37°C, categorizing it as mesophilic. It is characterized by having a single replicon and two membranes. This strain has a diverse range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and various other species across multiple taxa such as mammals, reptiles, and even plants like Solanum lycopersicum (tomatoes) and Brassica oleracea var. italica (broccoli). The ability of E. coli A240 to inhabit a variety of host organisms highlights its adaptability and potential for establishing complex biotic relationships. E. coli A240 is associated with a wide spectrum of health effects, particularly in humans, where it can cause conditions such as urinary tract infections (UTIs), gastrointestinal infections, and even severe complications like hemolytic uremic syndrome (HUS). Its pathogenicity is primarily linked to human hosts, indicating its significance in clinical microbiology and public health. The ecological insight derived from E. coli A240's wide host range and pathogenic potential suggests its role in both environmental and health-related contexts. Its presence in various hosts underscores the importance of monitoring this strain to mitigate its impact on health and understand its ecological dynamics within different environments.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain A240

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain A240
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain A240

Gene Summary

Adenine Count

1252467 bp

Thymine Count

1251742 bp

Guanine Count

1263020 bp

Cytosine Count

1280235 bp

Genome Length

5047464 bp

Protein-coding Genes

4657 genes

Non-Coding Genes

228 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
gamma-glutamyl-gamma-aminobutyrate hydrolaseFIM11_13690Not AvailableNegative2862489 - 286325328014.7
glutamine synthetaseFIM11_13695Not AvailablePositive2863465 - 286488353180.2
hypothetical proteinFIM11_13700Not AvailablePositive2865032 - 28651965971.24
putrescine/proton symporter puupFIM11_13705Not AvailablePositive2865186 - 286657150869.9
duf2543 family proteinFIM11_13710Not AvailablePositive2866705 - 28669509321.8
peptide abc transporter substrate-binding protein sapaFIM11_13715Not AvailablePositive2867263 - 286890661569.1
peptide abc transporter permease sapbFIM11_13720Not AvailablePositive2868903 - 286986836040.2
peptide abc transporter permease sapcFIM11_13725Not AvailablePositive2869855 - 287074531550.0
peptide abc transporter atp-binding protein sapdFIM11_13730Not AvailablePositive2870745 - 287173737662.9
peptide abc transporter atp-binding protein sapfFIM11_13735Not AvailablePositive2871739 - 287254530571.5

Displaying genes 2791 – 2800 of 4885 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total