Escherichia coli strain KCJK8463

Escherichia coli strain KCJK8463 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic and exhibits mobility due to the presence of flagella. This strain is classified as mesophilic, with an optimal growth temperature of 37°C. It is characterized by its ability to exist in pairs or singles and has a unique biotic relationship as a free-living organism. KCJK8463 is associated with a diverse range of hosts, including Homo sapiens, various livestock species such as Bos taurus and Sus scrofa, as well as avian species and even invertebrates like Apis mellifera and Acanthamoeba. This wide host range reflects its adaptability and ecological versatility. The strain is notable for its pathogenic potential, being linked to a variety of health effects in humans, including urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis. It is implicated in severe conditions such as hemolytic uremic syndrome (HUS), peritonitis, and foodborne infections, highlighting its relevance in clinical microbiology. In summary, E. coli strain KCJK8463 exemplifies the complexity of microbial interactions within host environments, serving as both a commensal and a pathogen. Its capacity to thrive in multiple hosts and cause significant health issues underscores the importance of monitoring this strain in both clinical and environmental contexts. Understanding its pathogenic mechanisms could provide insights into prevention and treatment strategies for associated diseases.