Escherichia coli strain KCJK8465

Escherichia coli strain KCJK8465 is a Gram-negative, rod-shaped bacterium characterized by its mobility and presence of flagella. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. It typically resides in host-associated habitats, demonstrating a free-living biotic relationship with a diverse range of hosts, including Homo sapiens, Gallus gallus, Bos taurus, and various other vertebrates and invertebrates. Optimal growth occurs at 37°C, indicating its mesophilic nature. KCJK8465 possesses a single replicon and is encapsulated by two membranes, typical of Gram-negative bacteria. The strain is associated with numerous health issues, particularly in humans, including urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). These health effects underscore its pathogenic potential, particularly in vulnerable populations. The presence of E. coli strain KCJK8465 in a variety of hosts suggests its ecological versatility and adaptability. Given its role in numerous diseases, it highlights the importance of monitoring and managing E. coli strains in both human health and agricultural contexts. The strain's association with multiple species, including livestock and humans, further emphasizes the interconnectedness of ecosystems and the potential for zoonotic disease transmission. Understanding the pathogenic mechanisms of such strains is crucial for developing effective prevention and treatment strategies.