Escherichia coli strain KCJK8483

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8483 is a Gram-negative, rod-shaped bacterium known for its facultative anaerobic metabolism. This strain typically exists in pairs or singles and is motile, possessing flagella that enable movement. As a mesophilic organism, it thrives optimally at 37°C but can adapt within a broader temperature range. KCJK8483 is host-associated and displays a free-living biotic relationship, being found in a diverse array of hosts including Homo sapiens (humans), Gallus gallus (domestic chickens), Bos taurus (cattle), and various other mammals, birds, and even plants like Solanum lycopersicum (tomato). This extensive host range suggests its ecological versatility and adaptability in different environments. The strain is associated with numerous health complications, primarily affecting humans and other animals. Notable health effects include urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and severe conditions such as hemolytic uremic syndrome (HUS) and septicemia. The propensity of KCJK8483 to cause a variety of infections points to its pathogenicity, particularly in humans. Understanding the traits of E. coli strain KCJK8483 is crucial for public health, as it illustrates the bacterium's ability to thrive in varied habitats while posing significant health risks. The strain's associations with both human and animal hosts highlight its potential role in zoonotic disease transmission and the importance of monitoring such pathogens in ecological and clinical contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8483

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8483
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8483 NODE_535_length_202_cov_4.186667,

Gene Summary

Adenine Count

1326368 bp

Thymine Count

1334894 bp

Guanine Count

1364565 bp

Cytosine Count

1368070 bp

Genome Length

5393940 bp

Protein-coding Genes

5194 genes

Non-Coding Genes

262 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
flagellar type iii secretion system pore protein flipFIB76_16190Not AvailableNegative3300738 - 330147526930.1
flagellar type iii secretion system protein flioFIB76_16195Not AvailableNegative3301475 - 330184012666.6
flagellar motor switch protein flinFIB76_16200Not AvailableNegative3301843 - 330225614811.7
flagellar motor switch protein flimFIB76_16205Not AvailableNegative3302253 - 330325737865.5
flagellar basal body-associated protein flilFIB76_16210Not AvailableNegative3303262 - 330372617266.9
flagellar hook length control protein flikFIB76_16215Not AvailableNegative3303831 - 330495839262.0
flagella biosynthesis chaperone flijFIB76_16220Not AvailableNegative3304955 - 330539817325.6
flagellum-specific atp synthase fliiFIB76_16225Not AvailableNegative3305417 - 330679049332.6
flagellar assembly protein flihFIB76_16230Not AvailableNegative3306790 - 330747625080.6
flagellar motor switch protein fligFIB76_16235Not AvailableNegative3307469 - 330846436778.2

Displaying genes 3311 – 3320 of 5456 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total