Escherichia coli strain KCJK8509

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8509 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic lifestyle, allowing it to thrive in both aerobic and anaerobic environments. This strain is characterized by its capability to move due to the presence of flagella and typically arranges itself in pairs or singles. It has been identified as a mesophilic organism with an optimal growth temperature of 37°C. The habitat of KCJK8509 is primarily host-associated, indicating a close relationship with various hosts, including Homo sapiens, Gallus gallus, and Bos taurus, among others. This strain is free-living, suggesting it can exist independently of its hosts as well. The extensive list of hosts includes a diverse range of taxa, such as mammals, birds, and even some plant species like Solanum lycopersicum and Brassica oleracea var. italica. KCJK8509 is notable for its significant health implications, being associated with numerous conditions such as urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and foodborne illnesses. The strain is linked to severe health outcomes, including hemolytic uremic syndrome (HUS) and septicemia, highlighting its pathogenic potential in humans and other animals. The ecological insight from the traits of KCJK8509 reflects its adaptability and versatility, allowing it to thrive in varied environments and interact with multiple hosts. This adaptability not only enhances its survival but also underscores the importance of monitoring such strains due to their implications for public health and animal health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8509

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8509
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8509 NODE_403_length_214_cov_6.747126,

Gene Summary

Adenine Count

1260560 bp

Thymine Count

1253664 bp

Guanine Count

1300558 bp

Cytosine Count

1295661 bp

Genome Length

5110453 bp

Protein-coding Genes

4715 genes

Non-Coding Genes

261 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
anaerobic nitric oxide reductase flavorubredoxinFIB83_02280Not AvailablePositive484585 - 48602454224.0
nadh:flavorubredoxin reductase norwFIB83_02285Not AvailablePositive486021 - 48715441334.1
carbamoyltransferase hypfFIB83_02290Not AvailableNegative487380 - 48963281833.4
electron transport protein hydnFIB83_02295Not AvailableNegative489785 - 49031219027.2
laci family dna-binding transcriptional regulatorFIB83_02300Not AvailableNegative490461 - 49147436932.5
pts cellobiose/arbutin/salicin transporter subunit iibcFIB83_02305Not AvailablePositive491731 - 49318851192.3
6-phospho-beta-glucosidaseFIB83_02310Not AvailablePositive493197 - 49462153786.6
hydrogenase maturation peptidase hyciFIB83_02315Not AvailableNegative494780 - 49525017057.6
formate hydrogenlyase maturation protein hychFIB83_02320Not AvailableNegative495243 - 49565315465.5
formate hydrogenlyase subunit hycgFIB83_02325Not AvailableNegative495650 - 49641728013.8

Displaying genes 631 – 640 of 4976 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total