Escherichia coli strain KCJK8577

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8577 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in a variety of environments. This strain is notable for its mobility, facilitated by the presence of flagella, and typically exists in pairs and singles. It is mesophilic, with an optimal growth temperature of 37°C, which aligns with the body temperature of its primary hosts. The strain is predominantly host-associated, found in a diverse array of species including Homo sapiens, Gallus gallus, Bos taurus, and various others across multiple taxa such as Mammalia, Aves, and even plants like Solanum lycopersicum. Its wide host range emphasizes its ecological versatility and adaptability. E. coli strain KCJK8577 is implicated in numerous health issues, particularly in humans. It is associated with urinary tract infections (UTIs), gastrointestinal infections, and serious conditions such as septicemia and neonatal meningitis. The strain's pathogenicity is significant, contributing to conditions such as hemorrhagic colitis, hemolytic uremic syndrome (HUS), and various forms of foodborne infections. The presence of this strain in both human and animal hosts underlines its role in zoonotic disease transmission and food safety, highlighting the importance of monitoring and controlling E. coli strains in agricultural and clinical settings. The broad spectrum of health effects associated with KCJK8577 illustrates the potential risks it poses, necessitating further research into its pathogenic mechanisms and environmental interactions.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8577

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8577
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8577 NODE_790_length_220_cov_2.860215,

Gene Summary

Adenine Count

1110643 bp

Thymine Count

1116898 bp

Guanine Count

1179575 bp

Cytosine Count

1174467 bp

Genome Length

4581588 bp

Protein-coding Genes

4427 genes

Non-Coding Genes

91 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
duf3461 family proteinFIB98_00200Not AvailablePositive40077 - 4046315097.0
cdar family transcriptional regulatorFIB98_00205Not AvailableNegative40552 - 4170943660.1
serine endoprotease degpFIB98_00210Not AvailableNegative41864 - 4328849357.3
dgtpaseFIB98_00215Not AvailableNegative43418 - 4493559362.1
5'-methylthioadenosine/s-adenosylhomocysteine nucleosidaseFIB98_00220Not AvailablePositive45019 - 4571724355.4
vitamin b12 abc transporter substrate-binding protein btufFIB98_00225Not AvailablePositive45710 - 4651029368.4
tric cation channel family proteinFIB98_00230Not AvailablePositive46548 - 4717122129.1
iron-sulfur cluster insertion protein erpaFIB98_00235Not AvailableNegative47218 - 4756212101.2
hypothetical proteinFIB98_00240Not AvailableNegative47555 - 476202329.94
h(+)/cl(-) exchange transporter clcaFIB98_00245Not AvailableNegative47644 - 479028817.96

Displaying genes 51 – 60 of 4518 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total