Escherichia coli strain KCJK8592

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8592 is a Gram-negative, rod-shaped bacterium characterized by its ability to arrange in pairs and singles. This strain is classified as a facultative anaerobe, allowing it to thrive in varying oxygen conditions. It is motile, possessing flagella, and has an optimal growth temperature of 37°C, fitting within the mesophilic temperature range. KCJK8592 is a free-living organism associated with various hosts, including Homo sapiens, Gallus gallus, Bos taurus, and many others across diverse taxa such as mammals, birds, and even plants like Solanum lycopersicum. This strain is notable for its significant health impacts, being associated with a range of infections in humans and other hosts. It has been linked to urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and more severe conditions such as septicemia and hemolytic uremic syndrome (HUS). The wide array of health effects underscores its pathogenic potential, particularly in humans where it is a common cause of foodborne illnesses and severe gastrointestinal diseases. The ecological insight from the data indicates that E. coli strain KCJK8592 has a versatile ecological niche, being able to colonize both animal hosts and various environments. Its association with multiple host species suggests a complex interplay in microbial ecosystems, highlighting the importance of understanding such pathogens in the context of public health and environmental microbiology. The strain's capacity for pathogenicity in humans emphasizes the need for ongoing surveillance and research to mitigate its health impacts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8592

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8592
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8592

Gene Summary

Adenine Count

1122943 bp

Thymine Count

1120093 bp

Guanine Count

1172809 bp

Cytosine Count

1165724 bp

Genome Length

4581572 bp

Protein-coding Genes

4378 genes

Non-Coding Genes

166 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
two-component system sensor histidine kinase rcscFIC02_02605Not AvailableNegative553163 - 556012106529.0
two-component system sensor histidine kinase atosFIC02_02610Not AvailablePositive556179 - 55800567763.1
acetoacetate metabolism transcriptional regulator atocFIC02_02615Not AvailablePositive558002 - 55938752179.6
acetate coa-transferase subunit alphaFIC02_02620Not AvailablePositive559583 - 56024523527.7
coa transferase subunit bFIC02_02625Not AvailablePositive560245 - 56089522942.0
tigr00366 family proteinFIC02_02630Not AvailablePositive560892 - 56221447530.6
acetyl-coa c-acetyltransferaseFIC02_02635Not AvailablePositive562245 - 56342940354.9
duf2135 domain-containing proteinFIC02_02640Not AvailableNegative563503 - 56427928231.2
duf2300 domain-containing proteinFIC02_02645Not AvailableNegative564284 - 56593361493.1
duf1175 domain-containing proteinFIC02_02655Not AvailableNegative570472 - 57109523768.5

Displaying genes 601 – 610 of 4544 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total