Escherichia coli strain KCJK8610

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8610 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in varied oxygen environments. It typically occurs in pairs or as single cells and possesses flagella, granting it motility. This strain is mesophilic, with an optimal growth temperature of 37°C, which aligns with the human body temperature, reflecting its host-associated habitat. E. coli KCJK8610 is free-living and has a diverse range of hosts, including Homo sapiens, various animal species such as Gallus gallus (chickens), Bos taurus (cattle), and Canis lupus familiaris (dogs). Additionally, it can inhabit plant species like Solanum lycopersicum (tomatoes) and Brassica oleracea var. italica (broccoli), showcasing its ecological versatility. This strain is associated with numerous health effects in humans, including urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as septicemia and hemolytic uremic syndrome (HUS). Its pathogenicity is well-documented, indicating its ability to cause various diseases, including neonatal meningitis and foodborne infections. The wide array of hosts and the pathogenic potential of E. coli KCJK8610 highlight its ecological significance as both a commensal organism and a pathogen. Its interactions with different hosts underscore the importance of understanding microbial dynamics in health, agriculture, and food safety, as well as in developing strategies to mitigate its associated health risks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8610

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8610
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8610 NODE_665_length_201_cov_0.662162,

Gene Summary

Adenine Count

1316875 bp

Thymine Count

1319196 bp

Guanine Count

1364458 bp

Cytosine Count

1357555 bp

Genome Length

5358214 bp

Protein-coding Genes

5208 genes

Non-Coding Genes

229 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
aspartate 1-decarboxylaseFIC06_00450Not AvailableNegative105395 - 10577513834.5
rpn family recombination-promoting nuclease/putative transposaseFIC06_00455Not AvailablePositive106049 - 10695134694.9
pantoate--beta-alanine ligaseFIC06_00460Not AvailableNegative107025 - 10787631629.6
3-methyl-2-oxobutanoate hydroxymethyltransferaseFIC06_00465Not AvailableNegative107888 - 10868228181.0
fimbrial-like adhesinFIC06_00470Not AvailableNegative108795 - 11006946411.3
fimbrial protein stafFIC06_00475Not AvailableNegative110122 - 11071821451.7
fimbrial-like protein yadlFIC06_00480Not AvailableNegative110745 - 11134720898.7
fimbrial proteinFIC06_00485Not AvailableNegative111362 - 11193120292.1
outer membrane usher proteinFIC06_00490Not AvailableNegative111948 - 11454895664.8
fimbrial chaperoneFIC06_00495Not AvailableNegative114583 - 11532326946.1

Displaying genes 251 – 260 of 5437 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total