Escherichia coli strain KCJK8638

Escherichia coli strain KCJK8638 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe. This strain typically exists in pairs or singles and possesses flagella, enabling its mobility. It thrives optimally at 37°C within a mesophilic temperature range. The strain has a single replicon and two membranes, indicative of its cellular structure. KCJK8638 is host-associated, exhibiting a free-living biotic relationship and can inhabit a wide range of hosts, including Homo sapiens, Gallus gallus, Bos taurus, and various other vertebrates, invertebrates, and even plants such as Solanum lycopersicum and Brassica oleracea var. italica. This strain is notably pathogenic to humans, associated with a myriad of health effects, including urinary tract infections (UTIs), gastrointestinal infections, septicemia, and neonatal meningitis, among others. The extensive pathogenic potential of KCJK8638 highlights its role in significant health issues, including hemolytic uremic syndrome (HUS) and colorectal cancer. The ecological insight from the presence of KCJK8638 in diverse hosts suggests its adaptability and resilience in various environments, potentially impacting both human health and animal well-being. This adaptability may also contribute to its role in foodborne infections, underscoring the importance of monitoring and understanding this strain within clinical and agricultural contexts.