Escherichia coli strain KCJK8658

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8658 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe. This strain exhibits mobility due to the presence of flagella and is typically found in pairs or singles. Its optimal growth temperature is 37°C, indicating a mesophilic lifestyle, which aligns with its host-associated habitat. This strain has a diverse array of known hosts, including Homo sapiens, various domestic animals such as Gallus gallus (chickens), Bos taurus (cattle), and Sus scrofa (pigs), as well as other vertebrates and invertebrates, such as Apis mellifera (honeybees) and Zophobas morio (mealworms). The wide host range suggests that KCJK8658 has evolved to thrive in numerous ecological niches, potentially leading to varied interactions within these hosts. KCJK8658 is associated with multiple health effects, primarily in humans, where it can cause urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis, among other diseases. Its pathogenic potential includes severe conditions like hemolytic uremic syndrome (HUS) and septicemia, highlighting its role as a significant human pathogen. The ability of E. coli strain KCJK8658 to inhabit diverse environments and infect a range of hosts underscores its ecological versatility and adaptability. Its association with various health conditions in humans and animals emphasizes the importance of monitoring this strain in both clinical and environmental settings to mitigate its impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8658

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8658
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8658 NODE_420_length_202_cov_9.146667,

Gene Summary

Adenine Count

1175161 bp

Thymine Count

1182659 bp

Guanine Count

1216835 bp

Cytosine Count

1214080 bp

Genome Length

4788743 bp

Protein-coding Genes

4502 genes

Non-Coding Genes

164 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
duf3300 domain-containing proteinFIC13_00460Not AvailableNegative107355 - 10911265556.1
bifunctional aconitate hydratase 2/2-methylisocitrate dehydrataseFIC13_00465Not AvailablePositive109467 - 11206493503.4
upf0231 family proteinFIC13_00470Not AvailablePositive112239 - 11260113942.3
adenosylmethionine decarboxylaseFIC13_00475Not AvailableNegative112639 - 11343330386.3
polyamine aminopropyltransferaseFIC13_00480Not AvailableNegative113449 - 11431532323.2
hypothetical proteinFIC13_00485Not AvailableNegative114421 - 11476812854.4
multicopper oxidase cueoFIC13_00490Not AvailablePositive114934 - 11648456657.7
hypothetical proteinFIC13_00495Not AvailablePositive116702 - 1168937318.89
tryptophan permeaseFIC13_00500Not AvailableNegative116894 - 11813844379.2
dead/deah family atp-dependent rna helicaseFIC13_00505Not AvailableNegative118292 - 12018170550.5

Displaying genes 171 – 180 of 4666 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total