Escherichia coli strain KCJK8666

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8666 is a Gram-negative, rod-shaped bacterium that can exist in pairs or as single cells. It is classified as a facultative anaerobe, indicating its ability to thrive in both aerobic and anaerobic environments, with an optimal growth temperature of 37°C, placing it within the mesophilic range. This strain possesses flagella, allowing for motility, and is characterized by a biotic relationship as free-living. KCJK8666 is associated with a variety of hosts, including Homo sapiens, various domestic animals (e.g., Gallus gallus, Bos taurus, Sus scrofa), and a range of other organisms such as Acanthamoeba, Apis mellifera, and even some plants like Solanum lycopersicum. This diverse host range suggests that KCJK8666 may have significant ecological interactions, potentially acting as a pathogen across multiple species. The strain is notably pathogenic to humans, contributing to a wide array of health issues, including urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and severe conditions such as hemolytic uremic syndrome (HUS) and septicemia. The presence of KCJK8666 in various hosts highlights its potential role in zoonotic transmission and foodborne infections, underscoring its importance in public health. Understanding the traits and pathogenicity of E. coli strain KCJK8666 is crucial for developing strategies to mitigate its health impacts, particularly in the context of food safety and disease prevention in both humans and animals.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8666

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8666
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8666

Gene Summary

Adenine Count

33058 bp

Thymine Count

33154 bp

Guanine Count

26994 bp

Cytosine Count

26915 bp

Genome Length

120121 bp

Protein-coding Genes

4359 genes

Non-Coding Genes

218 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
xanthine dehydrogenase fad-binding subunit xdhbFIC15_20820Not AvailablePositive4241010 - 424188831548.6
xanthine dehydrogenase iron sulfur-binding subunit xdhcFIC15_20825Not AvailablePositive4241885 - 424236416850.7
sigma-54-dependent transcriptional regulatorFIC15_20830Not AvailableNegative4242404 - 424418266085.0
1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomeraseFIC15_20835Not AvailableNegative4244389 - 42445194755.63
imidazole glycerol phosphate synthase subunit hishFIC15_20840Not AvailableNegative4244519 - 424510921654.1
bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase hisbFIC15_20845Not AvailableNegative4245109 - 424617640282.3
histidinol-phosphate transaminaseFIC15_20850Not AvailableNegative4246176 - 424724639362.3
histidinol dehydrogenaseFIC15_20855Not AvailableNegative4247243 - 424854746167.9
atp phosphoribosyltransferaseFIC15_20860Not AvailableNegative4248553 - 424945233368.8
his operon leader peptideFIC15_20865Not AvailableNegative4249598 - 42496482081.43

Displaying genes 4081 – 4090 of 4577 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total