Escherichia coli strain KCJK8700

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8700 is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe. It is capable of existing in both aerobic and anaerobic environments, with optimal growth at 37°C, placing it within the mesophilic temperature range. This strain is motile and possesses flagella, enabling its movement in various environments. KCJK8700 is primarily host-associated and exhibits a free-living biotic relationship, with a broad range of hosts, including Homo sapiens, Gallus gallus, Bos taurus, and various vertebrates, as well as plants like Solanum lycopersicum and Brassica oleracea var. italica. The strain contains one replicon and is surrounded by two membranes, typical of Gram-negative bacteria. This strain is notably associated with numerous health effects, particularly in humans, where it is implicated in urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as hemorrhagic colitis and hemolytic uremic syndrome (HUS). Other health impacts include neonatal meningitis, septicemia, and foodborne infections. The presence of KCJK8700 in diverse environments and its pathogenic potential underscore its role in both human health and disease ecology. The extensive list of hosts and health effects associated with KCJK8700 highlights the strain's adaptability and pathogenicity, suggesting its potential as a significant public health concern and an indicator of environmental contamination in ecosystems where it is found. This adaptability may facilitate its spread and impact on various biological systems, emphasizing the importance of monitoring and studying such strains in microbiological research.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8700

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8700
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8700

Gene Summary

Adenine Count

1164982 bp

Thymine Count

1164049 bp

Guanine Count

1195743 bp

Cytosine Count

1211620 bp

Genome Length

4736394 bp

Protein-coding Genes

4361 genes

Non-Coding Genes

270 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
duf4411 family proteinFIC21_23530Not AvailableNegative4705519 - 470587413830.5
imma/irre family metallo-endopeptidaseFIC21_23535Not AvailableNegative4705871 - 470664729174.1
Trna-alaNot AvailableNot AvailablePositive4707508 - 4707583Not Available
Trna-ileNot AvailableNot AvailablePositive4707626 - 4707702Not Available
type vi secretion system tube protein hcpFIC21_23555Not AvailablePositive4707750 - 470876138388.2
elongation factor tuFIC21_23560Not AvailablePositive4708849 - 470991539230.2
elongation factor tuFIC21_23565Not AvailablePositive4709916 - 47100614965.29
preprotein translocase subunit seceFIC21_23570Not AvailablePositive4710291 - 471067413644.3
transcription termination/antitermination protein nusgFIC21_23575Not AvailablePositive4710676 - 471094910580.9
2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthaseFIC21_23580Not AvailablePositive4710950 - 471142017206.3

Displaying genes 4581 – 4590 of 4631 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total